Molecular Cancer Research is proud to present this selection of recently published RAS articles.
- Biochemical and structural analysis of common cancer-associated KRAS mutations.
Hunter JC, Manandhar A, Carrasco MA, Gurbani D, Gondi S, Westover KD Molecular Cancer Research 2015. DOI:10.1158/1541-7786. MCR-15-0203. [Published OnlineFirst June 2, 2015]
- The key role of calmodulin in KRAS-driven adenocarcinomas.
Nussinov R, Muratcioglu S, Tsai CJ, Jang H, Gursoy A, Keskin O. Molecular Cancer Research 2015. DOI:10.1158/1541-7786.MCR-15-0165. [Published OnlineFirst June 17, 2015].
- Colorectal carcinogenesis: connecting K-RAS–induced transformation and CREB activity in vitro and in vivo.
Steven A, Heiduk M, Recktenwald CB, Hiebl B, Wickenhauser C, Massa C, et al. Molecular Cancer Research 2015;13:1248–62.
- AKT1 E17K in colorectal carcinoma is associated with BRAF V600E but not MSI-H status: a clinicopathologic comparison to PIK3CA helical and kinase domain mutants.
Hechtman JF, Sadowska J, Huse JT, Borsu L, Yaeger R, Shia J, et al. Molecular Cancer Research 2015;13:1003–8.
- Detection of tumor suppressor genes in cancer development by a novel shRNA-based method.
von Burstin J, Diersch S, Schneider G, Reichert M, Rustgi AK, Schmid RM. Molecular Cancer Research 2015;13:863–9.
- The RAS–membrane interface: isoform-specific differences in the catalytic domain.
Parker JA, Mattos C. Molecular Cancer Research 2015;13:595–603.
- Reversal of mutant KRAS-mediated apoptosis resistance by concurrent noxa/bik induction and Bcl-2/Bcl-xL antagonism in colon cancer cells.
Okamoto K, Zaanan A, Kawakami H, Huang S, Sinicrope FA. Molecular Cancer Research 2015;13:659–69.
- Adapting a drug screening platform to discover associations of molecular targeted radiosensitizers with genomic biomarkers.
Liu Q, Wang M, Kern AM, Khaled S, Han J, Yeap BY, et al. Molecular Cancer Research 2015;13:713–20.
- Loss of keratinocytic RXRα combined with activated CDK4 or oncogenic NRAS generates UVB-induced melanomas via loss of p53 and PTEN in the tumor microenvironment.
Coleman DJ, Chagani S, Hyter S, Sherman AM, Löhr CV, Liang X, et al. Molecular Cancer Research 2015;13:186–96.
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