Enhanced Growth of Pancreatic Tumors in SPARC-Null
Mice Is Associated With Decreased Deposition of Extracellular Matrix and Reduced Tumor Cell Apoptosis1
Supported in part by NIH grants (F32 HL10352 to R.A. Brekken and R01 GM40711 and R01 HL59574 to E.H. Sage), Gilbertson Foundation grant to the Hope Heart Institute, National Science Foundation grant (EEC-959161) to the University of Washington Engineered Biomaterials Center, American Cancer Society and Simmons Comprehensive Cancer Center Award (47411/56540 to R.A. Brekken), and Helsinki University Central Hospital Research Funds (EV0, Finland to P.A. Puolakkainen).
Note P.A. Puolakkainen and R.A. Brekken contributed equally to this work.