Table 3.

Distribution of truncating, ESS, nonsynonymous, and stop loss variants across each sample

Number of variants by consequence rank
Sample1234Total
1213437
2424652
3224549
483846
5724352
6737282
764652
8715664
91118193
107151158
1143741
1210291103
1396069
147262172
1832629
1973542
20413742
21915666
22535765
236396105
24213437
2544448
Total131251,24711,404
  • NOTE: Variants are listed according to their consequence: 1, truncating mutation (stop gained or frameshift); 2, ESS (essential splice-site mutation); 3, nonsynonymous mutation; 4, stop/loss mutation.