Table 6.

Ingenuity pathway analysis of genes mutated in stage 1 and recurrent aGCT

Ingenuity canonical pathways−Log (P)Ratio
Cell cycle control of chromosomal replication2.650.179
HER-2 signaling in breast cancer2.50.148
Endometrial cancer signaling2.210.156
DNA double-strand break repair by homologous recombination2.040.286
ErbB2-ErbB3 signaling2.030.147
EGF signaling2.030.147
  • NOTE: −log (P value) = −log10 = P value. Ratio (×100) = % of genes analyzed that are present in pathway.