Table 2.

IC50 concentration of FTD, 5-FU, and FdUrd in DLD1 and TK1 knockout cells

Cell linesFTD (μmol/L)5-FU (μmol/L)FdUrd (μmol/L)
DLD17.8 ± 1.603.80 ± 0.450.15 ± 0.05
DLD1-FTD>3003.70 ± 0.43>30
DLD1 TK1−/− #1-1>3005.00 ± 1.13>30
DLD1 TK1−/− #2-1>3004.90 ± 1.33>30