Table 1.

Lymph node metastasis in mouse models

Number of mice with LN+/total number
Control groupKeap1 OE group
3 weeks0/50/5
4 weeks0/50/5
5 weeks2/50/5
6 weeks4/51/5
  • NOTE: Lymph node metastasis of tumor cells was detected earlier in control A549 tumors than in A549-Keap1 tumors.

  • There were 2 mice and 4 mice detected lymph node metastasis in 5 weeks and 6 weeks, respectively, in the control group, and only 1 mouse detected lymph node metastasis in 6 weeks in the Keap1 OE group. LN+: positive lymph node metastasis.