Table 3.

The proportion of TGFβ signaling mutations in each mutation class

Score3′ UTR5′ UTRFrameshift DelFrameshift InsIn-frame DelIntronMissenseNonsenseSilentSplice site InsSplice site SNP
High TES0.530.130.010.030.280.010.01
Med TES0.330.100.050.020.010.040.370.040.020.0040.02
Low TES0.210.050.160.020.010.050.420.040.010.0040.02
  • NOTE: Data shown for CCLE mutations listed in Table 2.

  • Abbreviations: Del, deletion; Ins, insertion (ref. 28).