Table 4.

Association of H-Score based on protein expression of PLXDC2 and GNB3 and clinical and pathologic variables (Mann–Whitney test)

PLXDC2GNB3
VariablesMean rankPMean rankP
Histology
 SCC1/2-Verrucous38.040.4642.390.01*
 CC3-Basaloid33.8327.60
Invasion
 Superficial44.370 42.090.09
 Dermis deep26.4333.56
Vascular invasion
 Negative46.400.01 49.100.06
 Positive29.4136.53
Perineural invasion
 Negative44.220.03 45.790.79
 Positive27.4543.77
Lymph node metastasis
 Negative53.670.5157.930.61
 Positive57.9461.32
HPV infection
 Negative23.770.3029.100.24
 Positive28.1024.05
FIGO staging
 I–II66.270.4972.480.99
 III–IV71.0472.53