Table 1.

CI for the combination of mitomycin C and bortezomib under hypoxia (1% O2) was calculated using the CompuSyn software for LS174T and LS180 cancer cells

Combination therapyCI
Mitomycin C (μg/mL)Bortezomib (nmol/L)LS174TLS180
2100.24b0.25b
4200.41c0.33c
10300.47c0.41c
  • aSlight synergy.

    bStrong synergy.

  • cModerate synergy.