In vitro cytotoxicity values of ganetespib in bladder cancer cell lines
| Cell line | Ganetespib IC50 (nmol/L) | FGFR3 Status |
|---|---|---|
| DSH1 | 6 | WT |
| SW-1710 | 6 | WT |
| T24 | 7 | WT |
| RT112 | 9 | FGFR3-TACC3 |
| 639-V | 10 | R248C |
| SCaBER | 10 | WT |
| BFTC | 17 | WT |
| J82 | 18 | K652E |
| HT-1376 | 21 | WT |
| 647-V | 27 | WT |
| UM-UC3 | 33 | WT |
| LB831-BLC | 34 | WT |
| KU-19-19 | 36 | WT |
| 97-7 | 38 | S249C |
| 5637 | 44 | WT |
| HT-1197 | 53 | WT |
| MGH-U3 | 53 | Y375C |
| TCCSUP | 142 | WT |
| RT4 | 1733 | FGFR3-TACC3 |
| SW780 | 3451 | FGFR3-BAIAP2L1 |