Table 2.

Overview of the genes containing in their promoter, the SOX9-recognition sequence, and at the same time belong to the cluster of the genes which in LMET cells respond to hypoxia differently than in HMET cells

GeneMigrationSurvivalHMET/LMET (Hpx)HMET/LMET (Nmx)
MAP20.3950.082
SYNJ2+2.63.18
ETV1++4.295.7
SEMA3A+2.27.16
SEMA3C+3.66.87
WNT11+4.855.43
FOXC1++2.048.39
ITGA6++6.3610.63
HAS3+4.663,691
ERF+0.280.17
SMAD70.190.0011
ITGB8+2.979.78
FOXP10.440.46
LAMA3+2.32.38
ARHGAP210.30.22
HBEGF++16.2295.01
RASSF8+10.3416.34
CPEB40.220.24
PCDH170.0170.087
TBCCD1+2.716.62
CALD10.310.22
SGPP10.290.28
EREG++26.7226.17
NOV+19.566.49
SSH2+2.32.53
THBS10.370.31
GRB7++2.383.46
EHF+3.689.38
TPM10.120.0063
DUSP6++2179.2351,418
CAST+2.534.08
TIAM1++4.794.82
PIK3R1++3.435.66
PTPRR0.0000060.0013
LATS20.40.36
PPP2R2B0.280.13
SSBP30.450.37
HHEX+5.629.32
DEDD20.230.21
DOCK1+2.232.75
TNIK+3.433.14
ATF30.440.0093
SH3RF10.360.19
DLC10.340.4
SMAD3++4.235.94
IGFBP6++14.2230.48
HIF1AN+2.573.74
ETV5+5.438.57

NOTE: Relevance to cell migration and survival based on published data are indicated (+, increase; −, decrease) as well as differential expression shown as fold change between average value in HMET/LMET under normoxia or hypoxia, respectively.