Table 1.

Fold change in cytokine levels versus EMPTY

Cal-27SQ20B
CytokinesiNOX4EMPTY+ERLsiNOX4+ERLsiNOX4EMPTY+ERLsiNOX4+ERL
IL-21.0 ± 0.12.4 ± 0.1a1.3 ± 0.5bNDNDND
IL-40.9 ± 0.21.8 ± 0.2a1.0 ± 0.2b0.6 ± 0.5a1.7 ± 0.5a2.2 ± 2.4
IL-80.6 ± 0.1a1.0 ± 0.60.3 ± 0.2b1.0 ± 0.10.5 ± 0.12a0.2 ± 0.1
IL-10NDNDNDNDNDND
GM-CSF0.5 ± 0.1a0.9 ± 0.20.4 ± 0.1b1.0 ± 0.11.1 ± 1.00.6 ± 0.3b
IFN-γ1.0 ± 0.11.6 ± 0.4a0.9 ± 0.1b1.0 ± 0.12.6 ± 0.9a0.2 ± 0.3b
TNF-α0.8 ± 0.11.4 ± 0.8a0.7 ± 0.6bNDNDND

Abbreviation: ND, nondetectable.

  • aP < 0.05 vs. EMPTY.

  • bP < 0.05 vs. EMPTY + ERL.