Table 1.

TROY mRNA expression in invasive cells in vivo

GBM specimensR/C ratio
TB19516.9
VPJT0711.6
BTTB102010.3
BNI3645.1
VPJT032.5
BNI3712
BNI7582
BTTB8861.8
TB1871.6
JAP491.3
BNI90651.1
BNI6600.9
TB1860.9
VPJT010.9

NOTE: Quantitative RT-PCR (qRT-PCR) analysis of TROY mRNA levels from LCM glioma tumor core and rim cells (invasive edge) from cryopreserved biopsy specimens (n = 14). Levels of TROY mRNA were normalized to histone H3.3 and expressed as proportions of the mRNA levels of TROY in GBM cells residing in the tumor rim (R) compared in core (C). Nine of 14 GBM specimens (indicated by bold text) showed a 1.6- to 16.9-fold increase of TROY mRNA expression in the invading GBM cells at the rim relative to cells in the tumor core (P < 0.01).