Table 1.

Tumor formation by KRASG12D- and BRAFV600E-expressing Ink4a/Arf, Trp53 double null PDECs

Cells implantedTumor incidenceTime to tumor development (wks)Average tumor volume (SEM)
GFP1/68400 mm3 (±0)
KRASG12D6/641679 mm3 (±607)
BRAFV600E5/681197 mm3 (±430)

NOTE: Tumor volume calculated using the formula L × W × H.