Table 2.

Expression of STEAP mRNA and proteins in normal and cancer tissues

STEAP 1STEAP 2STEAP 3STEAP 4Reference
mRNAProteinmRNAProteinmRNAProteinmRNAProtein
Normal tissue
 Brain++++(1, 3, 6–8, 11, 14)
 Pituitary gland+(6)
 Fetal liver++++++(1, 3)
 Liver+++++++(1, 3, 6, 8, 10, 11, 14)
 Heart+++++(1, 3, 7, 8, 10, 11, 14)
 Trachea+(8)
 Lungs+++++(1, 3, 6, 8, 11, 14, 15)
 Thymus+++(1, 6)
 Lymph node(6)
 Bone marrow+++++++(1, 3, 6, 64)
 Thyroid gland(6)
 Adipose tissue+++(14, 41)
 Pancreas++++++++(1, 3, 6–8, 11, 14)
 Spleen(3, 6, 8, 14)
 Adrenal gland(6)
 Stomach++++(1, 6)
 Duodenum++++(1, 3)
 Small intestine++(8, 11)
 Colon++++(1, 3, 6, 8, 11)
 Kidney+++++++(1, 3, 7, 8, 14, 78)
 Bladder+++(6, 15, 78)
 Breast+++++(8, 12)
 Placenta++++++(1, 3, 6, 8, 10, 11, 14)
 Ovary++(6–8, 11)
 Fallopian tubes+(6)
 Uterus++(6, 8)
 Prostate++++++++++++(1, 3, 6–8, 11, 15)
 Testis++(6, 8, 11, 14)
 Ureter+(6)
 Skeletal muscle++++(1, 3, 6, 8, 10, 11, 14)
 Skin(6)
Cancer tissue
 Liver++++(69, 70)
 Lungs++(15)
 Colon+(6)
 Kidney++(78)
 Bladder++(6)
 Breast++(12)
 Prostate+++++++(6, 27, 77)
 Prostate lymph node metastasis+++(15)
 Prostate bone metastasis+++(15)

NOTE: Low levels, +; medium levels, ++; high levels, +++; not detectable, −.