Table 2.

Correlation of NEFL promoter methylation with clinical characteristics of patients with HNC

NEFL methylation analysis
Clinical variablesMethylatedUnmethylatedPa
No.2526
Age55.0 ± 19.3759.0 ± 16.23
Gender
 M1821
 F75NS
Locations
 Oral cavity1313
 Others1213NS
Differentiation
 Well and moderate1717
 Poor89NS
Node status
 N0913
 >N11613NS
Stages
 Early1113
 Late1413NS
Chemoresponseb
 Responsive619
 Nonresponsive1970.007

Abbreviation: NS, not significant.

  • aFisher exact test, 2-sided. (P > 0.05).

  • bCases with chemotherapy responses included responsive (completely and partially responsive) and nonresponsive (no response and progressive diseases).