Table 1.

Nomenclature and function of cohesin subunits

Generic nameSaccharomyces cerevisiaeSchizosaccharomyces pombeDrosophila melanogasterHomo sapiensFunction
Smc1SMC1psm1SMC1SMC1ACore cohesin subunit
Smc1βSMC1BCohesin subunit (meiosis)
Smc3SMC3psm3CapSMC3/CSPG6/BamacanCore cohesin subunit
Rad21MCD1/SCC1rad21Rad21RAD21Core cohesin subunit
Rec8REC8rec8c(2)MREC8Cohesin subunit (meiosis)
SA-1IRR1psc3SASTAG1Cohesin subunit
SA-2SCC3psc3SA2/StromalinSTAG2/StromalinCohesin subunit
SA-3rec11STAG3Cohesin subunit (meiosis)
NipblSCC2mis4Nipped-BNIPBLCohesin loading
Scc4 (or MAU-2, Caenorhabditis elegans)SCC4ssl3SCC4Cohesin loading
Esco1/2ECO1/CTF7eso1decoESCO1/2Acetyltransferases, establishment of cohesion
Pds5APDS5pds5pds5PDS5a
Pds5BPDS5b/APRIN/AS3Cohesin dissociation
WaplRAD61/WPL1waplwaplWAPALCohesin dissociation