Table 1.

Cytokines Involved in Induction of MET

MET-associated cytokinesaInducers or related elementsReference
FGFFGFR2bTransfection of FGFR2b expression construct(27, 28)
Exon IIIb(22, 23)
GCAUG element(29)
Fox-2(30)
Rbm35a, Rbm35b(31)
FGFR2cNon(21)
EGFEGFR/ErbB1; HER2/ErbB2EGFR kinase inhibitor(36, 78)
Inhibition of SHP2(38)
Erlotinib(39)
BMP2Alk2BMP2 siRNA(42)
BMP7Recombinant human BMP7(45–48)
WntWntRβ-catenin siRNA(51)
FZD7 siRNA(52, 53)
FZD4 siRNA(54)
WIF1(55)
AktPIA(57)
  • aCytokines and their corresponding receptors.