Table 1.

Data for the 3 sets of animal experiments with each primary GBM line

Primary GBM lineshControlMiceSEMshHuRMiceSEMP
Primary endpoint is tumor area mm2
D456985116251.50.0116
GBM1231581254.70.10
GBM61.050.060.0450.020.0001
Primary endpoint is number of distinct tumor foci
GBM641592.4540.0002

NOTE: When tumor size is the primary endpoint, a consistent size difference is seen following silencing of HuR (shHuR). GBM6 shows a very migratory behavior and a difference in tumor foci is quantified as a second primary endpoint.