Table 2.

Nek6 ISH signals were also higher in most of the patient tumor samples examined, with breast cancer tissues showing the highest elevation

TissueTumor typePositivePercentage
Breast details
    Invasive ductal carcinomas23/4156%
    Invasive lobular carcinomas2/4
Lung details
    Bronchioloalveolar carcinomas3/4
    Large cell carcinomas38%18/47

NOTE: A total of 169 formalin-fixed and paraffin-embedded human tumor samples were analyzed by ISH with [35S]UTP-labeled antisense and sense riboprobes of Nek6. Positive indicates ISH signals determined to be at least 2-fold higher in the tumor tissue compared with the adjacent normal sample.