Table 2.

Nek6 ISH signals were also higher in most of the patient tumor samples examined, with breast cancer tissues showing the highest elevation

TissueTumor typePositivePercentage
BreastCarcinomas25/4753%
ColonCarcinomas5/1338%
LungCarcinomas48/10944%
Breast details
    Invasive ductal carcinomas23/4156%
    Invasive lobular carcinomas2/4
Lung details
    Adenocarcinomas27/5847%
    Bronchioloalveolar carcinomas3/4
    Large cell carcinomas38%18/47

NOTE: A total of 169 formalin-fixed and paraffin-embedded human tumor samples were analyzed by ISH with [35S]UTP-labeled antisense and sense riboprobes of Nek6. Positive indicates ISH signals determined to be at least 2-fold higher in the tumor tissue compared with the adjacent normal sample.