Table 4.

In vivo Tumor Development Experiments in SCID Mice

Cell TypeCell Numbers InjectedTumor Incidence*Latency (d)
PLC8024 unsorted10,0000/3
100,0005/570
300,0008/858
CD133+ only5000/3
1,0002/385
10,0003/368
100,0004/449
300,0003/335
CD133+ ALDH+5003/382
1,0003/356
10,0003/345
100,0004/436
300,0006/622
CD133+ ALDH1,0000/3
10,0001/380
100,0002/460
300,0004/443
CD133 ALDH10,0000/3
100,0000/5
300,0001/585
  • NOTE: The table provides a summary of the in vivo tumor development experiments of different subpopulations sorted from the PLC8024 cell line in SCID mice.

  • * The number of tumors detected divided by the number of injections.

  • Approximate number of days from tumor cell injection to appearance of a tumor.