Table 1.

Conditioned Medium were Analyzed Using Antibody Arrays

Control1% Tob2% Tob4% Tob
sTNF Rll++++/−+/−
IGFBP3+
uPAR+
Angiogenin
GCSF
RANTES+/−+/−+/−+/−
GRO+/−+
IL-1ra++++++
bFGF++
MIP-1a++++
ICAM-1+
Osteoprotegerin+++
IGFBP4++++++++
IL-6++++++
MCP-1+/−+++++
TIMP-1+++++++
IL-8+/−++++++
TIMP-2++++++++++
  • NOTE: Secreted proteins significantly up-regulated by Tob are designated +, ++, or +++ (also indicated by progressively darker shading), whereas proteins showing little or no change are designated +/− or −.