Table 1.

Comparison of Amplification and Expression Levels of CCND3, CDC5L, and RUNX2 in Osteosarcoma Patient Samples

Tumor IDcCGH6p12-p21 Region-Specific Array
RNA Expression
Immunohistochemistry
CCND3CDC5LRUNX2CCND3CDC5LRUNX2CCND3CDC5LRUNX2
OS-13AmpNDNDNDNDNDND
OS-46GainNDNDNDNDNDND
OS-27LNCNCNCNCNDNDNDNDNDND
OS-68LAmpAmpAmpAmpNDNDNDNDNDND
OS-76LNCNCNCNCNDNDNDNDNDND
OS-79LAmpAmpAmpAmpNDNDNDNDNDND
OS-80LNCNCNCNCNDNDNDNDNDND
OS-82LNCNCNCNCNDNDNDNDNDND
OS-88LGainGainGainGainNDNDNDNDNDND
OS-161GainNDNDNDNDNDND
OS-196aAmpNDNDND
OS-197NCNCNCNCNDNDNDNDNDND
OS-204cAmpAmpAmpAmpNDNDND
OS-223NCNCNCNCNDNDND
OS-226cAmpNDNDNDNDNDND
OS-248AmpAmpAmpAmp
OS-274bAmpAmpAmpAmpNDNDND
OS-285NCGainGainGain
OS-295AmpAmpAmpAmpNDNDND
OS-307NCNCNCNCNDNDNDNDNDND
OS-311NCNCNCNCNDNDNDNDNDND
OS-355bAmpNDNDNDNDNDND
OS-361bAmpAmpAmpAmp
OS-363bAmpNDNDNDNDNDND
OS-364bAmpAmpAmpAmpNDNDNDNDNDND
OS-394NCNCNCNCNDNDNDNDNDND
OS-400GainGainGainGainNDNDNDNDNDND
OS-425GainGainGainGainNDNDNDNDNDND
OS-449aNCNDNDNDNDNDND
OS-464dAmpAmpAmpNDNDNDNDNDND
OS-501dAmpAmpAmpAmpNDNDNDNDNDND
OS-527GainGainGainGainNDNDNDNDNDND
OS-568NCNDNDNDNDNDND
OS-589AmpAmpAmpNDNDND
OS-606AmpNDNDNDNDNDND
OS-656GainNDNDNDNDNDND
  • NOTE: ▴, overexpression. Superscripts a, b, c, and d refer to tumor samples derived from the same patient.

  • Abbreviations: cCGH, chromosomal CGH; NC, no change; Amp, amplified; ND, not done.