Table 2.

Quantitative RT-PCR Analysis of ISG Expression in Senescing MDAH041 and Normal Fibroblast Cells Compared with Early PD Cells

MDAH041HCA2AFB-10
TLR3−1.247.8916.91
IFNα93.05−1.5411.47
IFNβ8.463.6125.99
IRF59.585.984.17
IRF73.4382.1425.99
STAT1α−1.6456.4930.06
  • NOTE: Expression levels of six ISGs in senescing MDAH041 cells (PD 23) were compared with early PD, nonsenescing MDAH041 cells (PD 13) by quantitative RT-PCR. Quantitative RT-PCR of those six ISGs was also done on senescing normal human fibroblasts HCA2 (PD 75) and AFB-10 cells (PD 21), whereas AFB-10 (PD 1) was used as nonsenescing normal control fibroblasts.