TABLE 4.

Expression of mSpry4 Does Not Affect β-Cell Tumor Progression

Age
8 wk
10 wk
12 wk
Dox treatmentWeek 5-8
Week 7-10
Week 10-12
Control*mSpry4Control*mSpry4Control*mSpry4
Normal/hyperplastic islets626234383235
Adenoma191821212020
818055595255
Carcinoma
G1151616161514
G23327223130
G3112321
192045414845
n = 213n = 217n = 219n = 224n = 161n = 218
N = 11N = 9N = 11N = 10N = 12N = 12
• NOTE: Values are given as percentage of total tumors. n, number of islets/tumors; N, number of mice.

• * Rip1Tag2/Rip1Tag2;Rip1rtTA/Rip1Tag2;(tetO)7mSpry4.

• Rip1Tag2;Rip1rtTA;(tetO)7mSpry4.