Table 1.

Categorical Distributions of Baseline Characteristics in All Patients and Associations with ADAM-15 Isoform Expression Levels

CharacteristicsADAM-15A*
ADAM-15B*
ADAM-15C
<Median>MedianP<Median>MedianP<Median>MedianP
Age (y)0.1480.6640.991
    ≤5031 (59)22 (41)28 (53)25 (47)26 (49)27 (51)
    >5083 (47)93 (53)87 (49)89 (51)86 (49)89 (51)
Menopausal status0.2100.2390.881
    Pre33 (57)25 (43)33 (57)25 (43)28 (48)30 (52)
    Post81 (47)90 (53)82 (48)89 (52)84 (49)86 (51)
Tumor size0.0930.6080.402
    pT129 (47)33 (53)31 (50)31 (50)26 (42)36 (58)
    pT262 (47)71 (53)64 (48)69 (52)67 (51)65 (49)
    pT3+421 (68)10 (32)18 (58)13 (42)17 (55)14 (45)
Histologic grade0.8280.1740.196
    1/239 (49)41 (53)46 (58)34 (42)39 (49)41 (51)
    341 (53)37 (47)39 (50)39 (50)33 (42)45 (58)
No. involved lymph nodes0.9560.1940.599
    046 (49)49 (52)45 (47)50 (53)42 (44)53 (56)
    1-335 (51)34 (49)41 (59)28 (41)32 (47)36 (53)
    ≥420 (49)21 (51)18 (44)23 (56)22 (54)19 (46)
NPI0.3250.1740.977
    13 (43)4 (57)5 (71)2 (29)3 (43)4 (57)
    242 (53)38 (47)51 (64)29 (36)33 (41)47 (59)
    317 (39)27 (61)21 (48)23 (52)19 (43)25 (57)
ER (fmol/mg protein)0.7430.1230.669
    <1038 (49)40 (51)34 (44)44 (56)39 (51)38 (49)
    ≥1076 (51)73 (49)81 (54)68 (46)71 (48)78 (52)
PgR (fmol/mg protein)0.8920.8080.174
    <1046 (51)45 (49)45 (49)46 (51)39 (43)51 (57)
    ≥1068 (50)69 (50)70 (51)67 (49)72 (53)65 (47)
  • Abbreviations: NPI, Nottingham Prognostic Index; ER, estrogen receptor; PgR, progesterone receptor.

  • * Number (percentage). Due to missing values, numbers do not always add up to 229.

  • Pearson χ2.