TABLE 1.

Accuracy of NIR-conPK11195 Tumor Detection

Pathologic result
PositiveNegative
Imaging result
    Positive103
    Negative519
Total1522
  • NOTE: A signal-to-noise ratio ≥4-fold was used as the criterion for predicting tumors in a cohort of 37 mice [Smad+/+ (n = 5), Smad3+/− (n = 7), Smad3−/− (n = 25)]. Imaging results were correlated with pathologic results upon sacrifice and analyzed using a contingency table as outlined in the table. Sensitivity, 10/15 (67%). Specificity, 19/22 (86%).