Table 1.

Summary of Tested Cell Lines with Respect to Constitutively Active STAT3

Cell lineOriginConstitutive phosphorylated STAT3Density phosphorylated STAT3
A375Melanoma√√
586Melanoma
729Melanoma√√
888MelanomaNoNo
1102Melanoma√√√√√
1286MelanomaNoNo
MelImMelanomaNoNo
MeWoMelanoma√√
Wm9Melanoma√√√√√
Wm35MelanomaNoNo
Wm239Melanoma√√
A431Cervix carcinoma√√√√√
HeLaCervix carcinoma
HepG2Liver carcinoma
HaCaTKeratinocyteNoNo
Hek293KidneyNoNo
NHDF212Dermal fibroblast(√)(√)
NHEMMelanocyteNoNo
  • NOTE: Increase of phosphorylated STAT3 signals as a result of high cell densities is indicated (number of “√” indicates the relative strength of phosphorylated STAT3 signals in Western blot analysis).