Table 3.

Microarray Analysis for Top 50 Differentially Expressed Genes between p53WT/WT and p53Val135/WT Mouse Normal Oral Tissues

GenbankGene nameSymbolFold change (P < 0.05) p53WT/WT/p53Val135/WT
NormalTumor
X02578Amylase 2, pancreaticAmy2−16.9
AB021961Transformation-related protein 53Trp53−9.6−14.6
AV380774Seminal vesicle secretion 6Svs6−9.4
AI183084Immunoglobulin heavy chain (γ polypeptide)Ighg−7.7
AA675031Transcribed sequence−5.9
AV301321Prolyl endopeptidasePrep−5.4
U03711Demilune cell and parotid proteinDcpp−5.3
X9994694-kb Genomic sequence encoding Tsx gene−4.8
AV334462Src homology 3 and cysteine-rich domainStac−4.8
AV227393Thymidine kinase 1Tk1−4.7
U15976Solute carrier family 27, member 1Slc27a1−4.6
L34808Caenorhabditis elegans ceh-10 homeodomain containing homologueChx10−4.6
L34570Arachidonate 15-lipoxygenaseAlox15−4.5
C76597Rho GTPase-activating protein 29Arhgap29−4.4
AI647632Transcribed sequence−4.3
AV209747Transcribed sequence−4.3
U30840Voltage-dependent anion channel 1Vdac1−4.3
AV031985Guanine nucleotide-binding protein (G protein), γ11Gng11−4.2
AV063979Fatty acid–binding protein 6, ileal (gastrotropin)Fabp6−4.2
D86603BTB and CNC homology 1Bach1−4.2
U59758p53-variant (p53) mRNAp53−4.2−4.1
AV371942Plakophilin 2Pkp2−4.1
X02801Glial fibrillary acidic proteinGfap−4.02.0
X05719CTL-associated protein 4Ctla4−3.9
AV232449Cadherin 15Cdh15−3.82.5
D87271ERK2 gene for extracellular signal-regulated kinase 2Erk22.9
M55669Proprotein convertase subtilisin/kexin type 2Pcsk23.0
L32973Thymidylate kinase homologue mRNA3.0
D88791Cysteine and glycine-rich protein 3Csrp33.1
AW122372TSPY-like 4, mRNA3.1
AF009513Plasma glutamate carboxypeptidasePgcp3.2
AV366872Selenium-binding protein 1Selenbp13.2
AV232606Early growth response 2Egr23.2
U96401Aldehyde dehydrogenase family 1, subfamily A7Aldh1a73.3
AV027236Insulin-like growth factor–binding protein, acid-labile subunitIgfals3.5
U75506BH3-interacting domain death agonistBid3.5
U09181Troponin I, cardiacTnni33.6
AB004639Fibroblast growth factor 18Fgf183.6
M83219S100 calcium-binding protein A9 (calgranulin B)S100a93.92.5
AF035717Transcription factor 21Tcf214.0
L27220Neuronal intermediate filament protein (α-internexin) gene4.1
AV002815CD68 antigenCd684.4
J03877Kallikrein 16Klk164.5
J00389Kallikrein 26Klk264.5
U68058Frizzled-related proteinFrzb4.7
U36760Forkhead box G1Foxg15.1−7.0
AJ224763Zinc finger protein 146Zfp1465.2
X58628Kallikrein 13Klk135.6
AJ006474Ca3 gene 5′-untranslated region and exon 15.8
X12972Myosin alkali light chain (exon 1)7.7−11.6