Table 2.

Cell Viability to Gemcitabine and Cisplatin

LC50GM637GM637-siRNAXP30ROXP30RO-EGFP-pol η
Gemcitabine (nmol/L)4.8 ± 0.23.0 ± 0.1 (3.5 ± 0.1)2.3 ± 0.15
Cisplatin (nmol/L)1,089 ± 11782 ± 30 (692 ± 31)381 ± 4614 ± 31 (736 ± 35)
  • NOTE: LC50 is defined as the concentration that inhibits 50% of cell growth. Results are mean ± SD from three independent experiments each conducted in triplicates. Numbers in parentheses are mean ± SD from two independent experiments each conducted in duplicates of trypan blue exclusion assay.