Table 1.

MAGE-A1, -A2, -A3, and -A12 Gene Expression in Different Cell Lines before and after Stimulation

Cell lineMAGE-A1
MAGE-A2
MAGE-A3
MAGE-A12
Basal5-Aza-CdRTrichostatin A5-Aza-CdR and trichostatin ABasal5-Aza-CdRTrichostatin A5-Aza-CdR and trichostatin ABasal5-Aza-CdRTrichostatin A5-Aza-CdR and trichostatin ABasal5-Aza-CdRTrichostatin A5-Aza-CdR and trichostatin A
Leukemic
    HL60(+)+++(+)+++++++++++++++++
Hepatic
    HepG2(+)(+)(+)(+)(+)
Prostate
    LNCaP(+)(+)+++(+)+++++(+)+++++++(+)(+)+++
    DU145+++(+)+++++(+)++++++(+)++++++
Breast
    BT20++++++++++++++++++++++++++++++++++++++++++++++++
    BT474++++++++++++++++++++++++++++++++++++++++++++++++
    MDA-MB-468++++++++++++++++++++++++++++++++++++++++++++++++
    T47D++++++++++++++++++++++++++++++++++++++++++++++++
    MCF-7(+)++++++++++++++++++
    GI101++++(+)+++++++++++
    MDA-MB-231++++++++++++++++++
    MTSV1.7(+)++++++++++(+)++++++++
Colon
    LoVo(+)++++++(+)+++++++++++++++++++
    Colo205++++++++++++++++++++
    WiDr++++++++++++++++++
  • NOTE: Cell lines were treated with 1 μmol/L 5-aza-CdR for 72 hours and/or with 0.5 μmol/L trichostatin A for the last 24 hours. −, none; (+), very weak; +, weak; ++, medium; +++, strong MAGE-A mRNA expression.