Table 2.

Clinicopathologic Characteristics of 25 Primary Breast and Matched Metastatic Lymph Node Specimens

Patient no.Age at DiagnosisHistologyTumor SizeNo. Positive Lymph NodesTNM stageClinical OutcomeFAI* in Primary TumorFAI in Lymph Node Metastasis
140IDCAT22IIBADF0.480.09
267IDCAT11IIADC0.300.25
360IDCAT22IIAADF0.000.17
469IDCAT21IIIBADF0.040.38
577ILCAT34IIIIADC0.590.18
681IDCAT31IIIADO0.170.14
761IDCAT21IIBADF0.580.00
870IDCAT28IIIADC0.440.00
930IDCAT36IIIAADF0.320.44
1060ILCAT24IIIAADF0.170.00
1163ILCAT1c4IIIAADF0.090.05
1276MixedT1b1IIAADF0.250.25
1348ILCAT22IIBADF0.240.00
1458IDCAT21IIBADF0.310.00
1565ILCAT1c26IIICAWD0.120.04
1673IDCAT21IIBADF0.160.09
1768IDCAT1b1IIAADF0.120.00
1880MixedT24IIIAADF0.330.25
1952IDCAT1c1IIAADF0.190.00
2047IDCAT21IIBADF0.600.08
2182IDCAT1c1IIAADF0.130.13
2246IDCAT17IIIAADF0.300.05
2348IDCAT219IIICADF0.040.04
2448IDCAT210IIICADF0.040.04
2573ILCAT210IIIAADF0.120.00
  • NOTE: Mixed = invasive mammary carcinoma with mixed ductal and lobular features.

    Abbreviations: IDCA, invasive ductal carcinoma; ILCA, invasive lobular carcinoma; ADF, alive disease-free; AWD, alive with disease; DC, deceased from cancer; DO, deceased, other; FAI, fractional allelic imbalance; TNM, tumor-node-metastasis.

  • * FAI calculated as the number of chromosomal regions showing AI divided by the number of informative genotypes.

  • Samples 1 to 8, archival; samples 9 to 25, CBCP.