Table 1.

Tumor Development in EpH4 Mammary Fat Pad Transplants Lung

CloneOutgrowth*TumorMetastasis
EpH4 pβP-Bcl-2-1913/160/160
EpH4 pβP-Bcl-2-2712/140/140
EpH4 pβP-Bcl-2-4718/220/220
EpH4 pβMEKDD-4722/2222/220
EpH4 pβMEKDD-11216/1616/160
EpH4 pβMEKDD-11616/1616/160
EpH4 pβMEKDD/Bcl-2-118/1818/185 ± 3
EpH4 pβMEKDD/Bcl-2-1316/1616/167 ± 5
EpH4 pβMEKDD/Bcl-2-2220/2020/2012 ± 6
  • * Outgrowth measured by whole mount analysis or by H&E staining of formalin-fixed transplanted mammary fat pads.

  • Metastasis scored by counting macroscopic metastatic lesions using a dissecting microscope. Values represent average ± SD.