Table 3.

Effect of ATRA on HL-60 Cell Differentiation as Evaluated by Means of CD11b Expression and Flow Cytometric Analysis

Cell TreatmentPercentage of Differentiated Cells
HL-60 PTHL-60 AR
None (control)6.6 ± 1.85.7 ± 1.1
24 h ATRA14.4 ± 2.15.8 ± 1.2
48 h ATRA28.7 ± 3.25.9 ± 1.4
72 h ATRA47.7 ± 4.96.1 ± 1.3
96 h ATRA83.5 ± 6.66.4 ± 1.1
  • Note: Data are expressed as means ± SD of three separate experiments and show the percentage of differentiated cells.