Table 1.

Comparison of Proliferation and Apoptosis in Mammary Epithelial Cells Between Transgenic and Wild-Type Mice at Day 16.5 of Pregnancy

Note: Numbers represent the average percentage of positive cells ± SD. TUNEL, terminal deoxynucleotidyl transferase (Tdt)-mediated dUTP nick end labeling.

StainingKi-67BrdUrdTUNEL
Transgenic25.9 ± 4.6%11.4 ± 1.9%*2.0 ± 0.4%**
Wild type17.2 ± 3.6%6.8 ± 0.87%*0.7 ± 0.2%**
  • * P < 0.02 (Student's t test).

  • ** P < 0.05 (Student's t test).