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Molecular Cancer Research
Molecular Cancer Research
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About the Cover

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Sorafenib, an oncogenic kinase inhibitor, is currently the sole treatment with demonstrated efficacy in liver cancer. In this issue, Galmiche and coworkers report that the proapoptotic protein BAD, a member of the BCL2 family, is a determinant of the cytotoxic effect of sorafenib on liver cancer cells. ABT-737, an inhibitor of proteins of the BCL2 family with a BAD-like reactivity, sensitizes liver cancer cells to the cytotoxic effect of sorafenib. For further details, please see Galmiche and colleagues on page 1116 in this issue.

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Molecular Cancer Research: 8 (8)
August 2010
Volume 8, Issue 8
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Issue Highlights

  • BAD, a Proapoptotic Member of the BCL2 Family, Is a Potential Therapeutic Target in Hepatocellular Carcinoma
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Molecular Cancer Research
eISSN: 1557-3125
ISSN: 1541-7786

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