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Table of Contents

Perspective

Perspective

Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research

Subha Madhavan, Jean-Claude Zenklusen, Yuri Kotliarov, Himanso Sahni, Howard A. Fine and Kenneth Buetow

Mol Cancer Res February 1 2009 7 (2) 157-167; DOI:10.1158/1541-7786.MCR-08-0435

Angiogenesis, Metastasis, and the Cellular Microenvironment

Angiogenesis, Metastasis, and the Cellular Microenvironment

CD44 Variant Isoforms Promote Metastasis Formation by a Tumor Cell-Matrix Cross-talk That Supports Adhesion and Apoptosis Resistance

Pamela Klingbeil, Rachid Marhaba, Thorsten Jung, Robert Kirmse, Thomas Ludwig and Margot Zöller

Mol Cancer Res February 1 2009 7 (2) 168-179; DOI:10.1158/1541-7786.MCR-08-0207
Angiogenesis, Metastasis, and the Cellular Microenvironment

Up-Regulation of Connective Tissue Growth Factor in Endothelial Cells by the Microtubule-Destabilizing Agent Combretastatin A-4

Jana Samarin, Margot Rehm, Bettina Krueger, Jens Waschke and Margarete Goppelt-Struebe

Mol Cancer Res February 1 2009 7 (2) 180-188; DOI:10.1158/1541-7786.MCR-08-0292
Angiogenesis, Metastasis, and the Cellular Microenvironment

EFEMP1 Expression Promotes In vivo Tumor Growth in Human Pancreatic Adenocarcinoma

Hendrik Seeliger, Peter Camaj, Ivan Ischenko, Axel Kleespies, Enrico N. De Toni, Susanne E. Thieme, Helmut Blum, Gerald Assmann, Karl-Walter Jauch and Christiane J. Bruns

Mol Cancer Res February 1 2009 7 (2) 189-198; DOI:10.1158/1541-7786.MCR-08-0132

Cancer Genes and Genomics

Cancer Genes and Genomics

Inactivation of the MAL Gene in Breast Cancer Is a Common Event That Predicts Benefit from Adjuvant Chemotherapy

Hisani N. Horne, Paula S. Lee, Susan K. Murphy, Miguel A. Alonso, John A. Olson Jr. and Jeffrey R. Marks

Mol Cancer Res February 1 2009 7 (2) 199-209; DOI:10.1158/1541-7786.MCR-08-0314
Cancer Genes and Genomics

Yin Yang 1 Modulates Taxane Response in Epithelial Ovarian Cancer

Noriomi Matsumura, Zhiqing Huang, Tsukasa Baba, Paula S. Lee, Jason C. Barnett, Seiichi Mori, Jeffrey T. Chang, Wen-Lin Kuo, Alison H. Gusberg, Regina S. Whitaker, Joe W. Gray, Shingo Fujii, Andrew Berchuck and Susan K. Murphy

Mol Cancer Res February 1 2009 7 (2) 210-220; DOI:10.1158/1541-7786.MCR-08-0255
Cancer Genes and Genomics

Yin Yang 1 Regulates the Expression of Snail through a Distal Enhancer

Matthew B. Palmer, Parimal Majumder, John C. Cooper, Hyesuk Yoon, Paul A. Wade and Jeremy M. Boss

Mol Cancer Res February 1 2009 7 (2) 221-229; DOI:10.1158/1541-7786.MCR-08-0229
Cancer Genes and Genomics

KRAS2 Mutations in Human Pancreatic Acinar-Ductal Metaplastic Lesions Are Limited to Those with PanIN: Implications for the Human Pancreatic Cancer Cell of Origin

Chanjuan Shi, Seung-Mo Hong, Phillip Lim, Hirohiko Kamiyama, Mehtab Khan, Robert A. Anders, Michael Goggins, Ralph H. Hruban and James R. Eshleman

Mol Cancer Res February 1 2009 7 (2) 230-236; DOI:10.1158/1541-7786.MCR-08-0206

DNA Damage and Cellular Stress Responses

DNA Damage and Cellular Stress Responses

p53 Mutant Human Glioma Cells Are Sensitive to UV-C-Induced Apoptosis Due to Impaired Cyclobutane Pyrimidine Dimer Removal

Luis F.Z. Batista, Wynand P. Roos, Bernd Kaina and Carlos F.M. Menck

Mol Cancer Res February 1 2009 7 (2) 237-246; DOI:10.1158/1541-7786.MCR-08-0428
DNA Damage and Cellular Stress Responses

REV1 Is Implicated in the Development of Carcinogen-Induced Lung Cancer

Chad A. Dumstorf, Suparna Mukhopadhyay, Elangovan Krishnan, Bodduluri Haribabu and W. Glenn McGregor

Mol Cancer Res February 1 2009 7 (2) 247-254; DOI:10.1158/1541-7786.MCR-08-0399

Signaling and Regulation

Signaling and Regulation

Anastellin, the Angiostatic Fibronectin Peptide, Is a Selective Inhibitor of Lysophospholipid Signaling

Anthony Ambesi and Paula J. McKeown-Longo

Mol Cancer Res February 1 2009 7 (2) 255-265; DOI:10.1158/1541-7786.MCR-08-0195
Signaling and Regulation

Annexin-1 Regulates Growth Arrest Induced by High Levels of Estrogen in MCF-7 Breast Cancer Cells

Emily Zhao-Feng Ang, Hung Thanh Nguyen, Hui-Ling Sim, Thomas C. Putti and Lina H.K. Lim

Mol Cancer Res February 1 2009 7 (2) 266-274; DOI:10.1158/1541-7786.MCR-08-0147
Signaling and Regulation

Expression of Epidermal Growth Factor Receptor or ErbB3 Facilitates Geldanamycin-Induced Down-Regulation of ErbB2

Nina Marie Pedersen, Kamilla Breen, Marianne Skeie Rødland, Camilla Haslekås, Espen Stang and Inger Helene Madshus

Mol Cancer Res February 1 2009 7 (2) 275-284; DOI:10.1158/1541-7786.MCR-07-2183