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Table of Contents

Subject Review

Subject Review

Pharmacogenetics and Regulation of Human Cytochrome P450 1B1: Implications in Hormone-Mediated Tumor Metabolism and a Novel Target for Therapeutic Intervention

Tristan M. Sissung, Douglas K. Price, Alex Sparreboom and William D. Figg

Mol Cancer Res March 1 2006 4 (3) 135-150; DOI:10.1158/1541-7786.MCR-05-0101

Angiogenesis, Metastasis, and the Cellular Microenvironment

Angiogenesis, Metastasis, and the Cellular Microenvironment

SSeCKS/Gravin/AKAP12 Metastasis Suppressor Inhibits Podosome Formation via RhoA- and Cdc42-Dependent Pathways

Irwin H. Gelman and Lingqiu Gao

Mol Cancer Res March 1 2006 4 (3) 151-158; DOI:10.1158/1541-7786.MCR-05-0252
Angiogenesis, Metastasis, and the Cellular Microenvironment

Activation of Peroxisome Proliferator-Activated Receptor-γ Decreases Pancreatic Cancer Cell Invasion through Modulation of the Plasminogen Activator System

Hirozumi Sawai, Joey Liu, Howard A. Reber, Oscar J. Hines and Guido Eibl

Mol Cancer Res March 1 2006 4 (3) 159-167; DOI:10.1158/1541-7786.MCR-05-0257

Cancer Genes and Genomics

Cancer Genes and Genomics

Genomic and Expression Analysis of the 3q25-q26 Amplification Unit Reveals TLOC1/SEC62 as a Probable Target Gene in Prostate Cancer

Volker Jung, Roland Kindich, Jörn Kamradt, Martin Jung, Mirko Müller, Wolfgang A. Schulz, Rainer Engers, Gerhard Unteregger, Michael Stöckle, Richard Zimmermann and Bernd Wullich

Mol Cancer Res March 1 2006 4 (3) 169-176; DOI:10.1158/1541-7786.MCR-05-0165

Cell Cycle, Cell Death, and Senescence

Cell Cycle, Cell Death, and Senescence

VRK1 Signaling Pathway in the Context of the Proliferation Phenotype in Head and Neck Squamous Cell Carcinoma

Claudio R. Santos, María Rodríguez-Pinilla, Francisco M. Vega, José L. Rodríguez-Peralto, Sandra Blanco, Ana Sevilla, Alberto Valbuena, Teresa Hernández, André J. van Wijnen, Fengzhi Li, Enrique de Alava, Montserrat Sánchez-Céspedes and Pedro A. Lazo

Mol Cancer Res March 1 2006 4 (3) 177-185; DOI:10.1158/1541-7786.MCR-05-0212

DNA Damage and Cellular Stress Responses

DNA Damage and Cellular Stress Responses

DNase II and the Chk2 DNA Damage Pathway Form a Genetic Barrier Blocking Replication of Horizontally Transferred DNA

Anna Bergsmedh, Jacob Ehnfors, Kohki Kawane, Noboru Motoyama, Shigekazu Nagata and Lars Holmgren

Mol Cancer Res March 1 2006 4 (3) 187-195; DOI:10.1158/1541-7786.MCR-05-0262
DNA Damage and Cellular Stress Responses

ATM Requirement in Gene Expression Responses to Ionizing Radiation in Human Lymphoblasts and Fibroblasts

Cynthia L. Innes, Alexandra N. Heinloth, Kristina G. Flores, Stella O. Sieber, Paula B. Deming, Pierre R. Bushel, William K. Kaufmann and Richard S. Paules

Mol Cancer Res March 1 2006 4 (3) 197-207; DOI:10.1158/1541-7786.MCR-05-0154

Signalling and Regulation

Signalling and Regulation

Transforming Growth Factor-β1 Induces Tissue Inhibitor of Metalloproteinase-1 Expression via Activation of Extracellular Signal-Regulated Kinase and Sp1 in Human Fibrosarcoma Cells

Hee-Jin Kwak, Myung-Jin Park, Hyeyoung Cho, Chang-Min Park, Sang-Ik Moon, Hyung-Chan Lee, In-Chul Park, Mi-Suk Kim, Chang Hun Rhee and Seok-Il Hong

Mol Cancer Res March 1 2006 4 (3) 209-220; DOI:10.1158/1541-7786.MCR-05-0140