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Molecular Cancer Research
Molecular Cancer Research
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About the Cover

Cover image

Cover image expansion

The use of oils as a carrier for lipophilic drugs during intraperitoneal injection is a common practice in biomedical research, but their differential effects on the microenvironment of the injection site has not been studied. The cover depicts macrophages incubated with vegetal oil, which induces cell death by either apoptosis or pyroptosis depending on the oil used (blue, live cells; green, apoptotic cells; red, necrotic cells). The authors conclude that careful selection of carrier oils based on experimental context is critical to the proper interpretation of data derived from intraperitoneal injection models. For more information, see the Highlight on page 165 and the article on page 288.

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Molecular Cancer Research: 19 (2)
February 2021
Volume 19, Issue 2
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Issue Highlights

  • Intraperitoneal Oil Application Causes Local Inflammation with Depletion of Resident Peritoneal Macrophages
  • Transcriptomic Analysis of Diffuse Intrinsic Pontine Glioma (DIPG) Identifies a Targetable ALDH-Positive Subset of Highly Tumorigenic Cancer Stem-like Cells
  • Aggressive B-cell Lymphoma with MYC/TP53 Dual Alterations Displays Distinct Clinicopathobiological Features and Response to Novel Targeted Agents
  • Breast Tumor Kinase (Brk/PTK6) Mediates Advanced Cancer Phenotypes via SH2-Domain Dependent Activation of RhoA and Aryl Hydrocarbon Receptor (AhR) Signaling
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Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Research
eISSN: 1557-3125
ISSN: 1541-7786

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