The Sustained Induction of c-MYC Drives Nab-Paclitaxel Resistance in Primary Pancreatic Ductal Carcinoma Cells

Erika Parasido; George S. Avetian; Aisha Naeem; Garrett Graham; Michael Pishvaian; Eric Glasgow; Shaila Mudambi; Yichien Lee; Chukwuemeka Ihemelandu; Muhammad Choudhry; Ivana Peran; Partha P. Banerjee; Maria Laura Avantaggiati; Kirsten Bryant; Elisa Baldelli; Mariaelena Pierobon; Lance Liotta; Emanuel Petricoin; Stanley T. Fricke; Aimy Sebastian; Joseph Cozzitorto; Gabriela G. Loots; Deepak Kumar; Stephen Byers; Eric Londin; Analisa DiFeo; Goutham Narla; Jordan Winter; Jonathan R. Brody; Olga Rodriguez; Chris Albanese

doi:10.1158/1541-7786.MCR-19-0191

Cancer Genes and Networks

The Sustained Induction of c-MYC Drives Nab-Paclitaxel Resistance in Primary Pancreatic Ductal Carcinoma Cells

Erika Parasido, George S. Avetian, Aisha Naeem, Garrett Graham, Michael Pishvaian, Eric Glasgow, Shaila Mudambi, Yichien Lee, Chukwuemeka Ihemelandu, Muhammad Choudhry, Ivana Peran, Partha P. Banerjee, Maria Laura Avantaggiati, Kirsten Bryant, Elisa Baldelli, Mariaelena Pierobon, Lance Liotta, Emanuel Petricoin, Stanley T. Fricke, Aimy Sebastian, Joseph Cozzitorto, Gabriela G. Loots, Deepak Kumar, Stephen Byers, Eric Londin, Analisa DiFeo, Goutham Narla, Jordan Winter, Jonathan R. Brody, Olga Rodriguez and Chris Albanese

Erika Parasido

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

George S. Avetian

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Aisha Naeem

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Garrett Graham

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Garrett Graham

Michael Pishvaian

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Eric Glasgow

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Shaila Mudambi

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yichien Lee

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Chukwuemeka Ihemelandu

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Muhammad Choudhry

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ivana Peran

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Ivana Peran

Partha P. Banerjee

2Department of Biochemistry, Molecular and Cell Biology, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Maria Laura Avantaggiati

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kirsten Bryant

3Department of Pharmacology, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kirsten Bryant

Elisa Baldelli

4Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Elisa Baldelli

Mariaelena Pierobon

4Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Lance Liotta

4Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Emanuel Petricoin

4Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Stanley T. Fricke

5Center for Translational Imaging, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Aimy Sebastian

6Biology and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, California.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Joseph Cozzitorto

7Division of Surgical Research, Department of Surgery, Jefferson Pancreas, Biliary and Related Cancer Center, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Gabriela G. Loots

6Biology and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, California.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Deepak Kumar

8Department of Pharmaceutical Sciences, Julius L. Chambers Biomedical/Biotechnology Research Institute (JLC-BBRI), North Carolina Central University, Durham, North Carolina.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Deepak Kumar

Stephen Byers

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Eric Londin

9Computational Medicine Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Analisa DiFeo

10Division of Genetic Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Analisa DiFeo

Goutham Narla

10Division of Genetic Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jordan Winter

7Division of Surgical Research, Department of Surgery, Jefferson Pancreas, Biliary and Related Cancer Center, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

11Case Western Reserve School of Medicine, Case Comprehensive Cancer Center and University Hospitals Cleveland Medical Center, Cleveland, Ohio.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jonathan R. Brody

7Division of Surgical Research, Department of Surgery, Jefferson Pancreas, Biliary and Related Cancer Center, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Olga Rodriguez

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

5Center for Translational Imaging, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Chris Albanese

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C.

5Center for Translational Imaging, Georgetown University Medical Center, Washington, D.C.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: albanese@georgetown.edu

DOI: 10.1158/1541-7786.MCR-19-0191 Published September 2019

Article
Figures & Data
Info & Metrics
PDF

Log in using your username and password

Username *

Password *

Forgot your user name or password?

Purchase access

You may purchase access to this article. This will require you to create an account if you don't already have one.

PreviousNext

September 2019
Volume 17, Issue 9

Table of Contents
Table of Contents (PDF)
About the Cover
Editorial Board (PDF)

Search for this keyword

View this article with LENS

Open full page PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for sharing this Molecular Cancer Research article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following The Sustained Induction of c-MYC Drives Nab-Paclitaxel Resistance in Primary Pancreatic Ductal Carcinoma Cells

Message Subject (Your Name) has forwarded a page to you from Molecular Cancer Research

Message Body (Your Name) thought you would be interested in this article in Molecular Cancer Research.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

The Sustained Induction of c-MYC Drives Nab-Paclitaxel Resistance in Primary Pancreatic Ductal Carcinoma Cells

Mol Cancer Res September 1 2019 (17) (9) 1815-1827; DOI: 10.1158/1541-7786.MCR-19-0191

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

The Sustained Induction of c-MYC Drives Nab-Paclitaxel Resistance in Primary Pancreatic Ductal Carcinoma Cells

Mol Cancer Res September 1 2019 (17) (9) 1815-1827; DOI: 10.1158/1541-7786.MCR-19-0191

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Jump to section

Article
Figures & Data
Info & Metrics
PDF

Main menu

User menu

Search

The Sustained Induction of c-MYC Drives Nab-Paclitaxel Resistance in Primary Pancreatic Ductal Carcinoma Cells

Purchase access

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Articles

Information for

About MCR