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Molecular Cancer Research
Molecular Cancer Research

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Cancer Genes and Networks

Identification of TP53RK-Binding Protein (TPRKB) Dependency in TP53-Deficient Cancers

Moloy T. Goswami, Kelly R. VanDenBerg, Sumin Han, Lei Lucy Wang, Bhavneet Singh, Travis Weiss, Myles Barlow, Steven Kamberov, Kari Wilder-Romans, Daniel R. Rhodes, Felix Y. Feng and Scott A. Tomlins
Moloy T. Goswami
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
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Kelly R. VanDenBerg
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
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Sumin Han
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
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Lei Lucy Wang
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
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Bhavneet Singh
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
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Travis Weiss
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
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Myles Barlow
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
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Steven Kamberov
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
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Kari Wilder-Romans
Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan.
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Daniel R. Rhodes
Compendia Biosciences, Ann Arbor, Michigan.
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Felix Y. Feng
Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan.
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Scott A. Tomlins
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan. Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan. Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan. Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan. Department of Urology, University of Michigan Medical School, Ann Arbor, Michigan.
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  • For correspondence: tomlinss@umich.edu
DOI: 10.1158/1541-7786.MCR-19-0144 Published August 2019
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Article Information

Volume 17, Issue 8, pp. 1652-1664

DOI 
https://doi.org/10.1158/1541-7786.MCR-19-0144
PubMed 
31110156

Published By 
American Association for Cancer Research
Print ISSN 
1541-7786
Online ISSN 
1557-3125
History 
  • Received February 6, 2019
  • Revision received March 28, 2019
  • Accepted May 14, 2019
  • Published first May 20, 2019.

Article Versions

  • Previous version (May 20, 2019 - 06:32).
  • Previous version (June 17, 2019 - 06:19).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2019 American Association for Cancer Research.

Author Information

  1. Moloy T. Goswami1,
  2. Kelly R. VanDenBerg1,
  3. Sumin Han1,
  4. Lei Lucy Wang1,
  5. Bhavneet Singh1,
  6. Travis Weiss1,
  7. Myles Barlow1,
  8. Steven Kamberov1,
  9. Kari Wilder-Romans3,
  10. Daniel R. Rhodes2,
  11. Felix Y. Feng3, and
  12. Scott A. Tomlins1,3,4,5,6,*
  1. 1Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
  2. 2Compendia Biosciences, Ann Arbor, Michigan.
  3. 3Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan.
  4. 4Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan.
  5. 5Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan.
  6. 6Department of Urology, University of Michigan Medical School, Ann Arbor, Michigan.
  1. ↵*Corresponding Author:
    Scott A. Tomlins, University of Michigan-Ann Arbor, 1500 E. Medical Center Dr., 7322 Cancer Center, Ann Arbor, MI 48109. Phone: 734-764-1549; Fax: 734-647-7950; E-mail: tomlinss{at}umich.edu
  1. M.T. Goswami and K.R. VanDenBerg contributed equally to this article

  • Current address for D.R. Rhodes: Strata Oncology, Ann Arbor, Michigan; and current address for F.Y. Feng, University of California San Francisco, San Francisco, California.

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Molecular Cancer Research: 17 (8)
August 2019
Volume 17, Issue 8
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Identification of TP53RK-Binding Protein (TPRKB) Dependency in TP53-Deficient Cancers
Moloy T. Goswami, Kelly R. VanDenBerg, Sumin Han, Lei Lucy Wang, Bhavneet Singh, Travis Weiss, Myles Barlow, Steven Kamberov, Kari Wilder-Romans, Daniel R. Rhodes, Felix Y. Feng and Scott A. Tomlins
Mol Cancer Res August 1 2019 (17) (8) 1652-1664; DOI: 10.1158/1541-7786.MCR-19-0144

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Identification of TP53RK-Binding Protein (TPRKB) Dependency in TP53-Deficient Cancers
Moloy T. Goswami, Kelly R. VanDenBerg, Sumin Han, Lei Lucy Wang, Bhavneet Singh, Travis Weiss, Myles Barlow, Steven Kamberov, Kari Wilder-Romans, Daniel R. Rhodes, Felix Y. Feng and Scott A. Tomlins
Mol Cancer Res August 1 2019 (17) (8) 1652-1664; DOI: 10.1158/1541-7786.MCR-19-0144
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