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Table of Contents

Highlights

Highlights

Highlights of This Issue

Mol Cancer Res March 1 2019 17 (3) 667-667;

Rapid Impact

Rapid Impact

Tyrosine Phosphorylation of p27Kip1 Correlates with Palbociclib Responsiveness in Breast Cancer Tumor Cells Grown in Explant Culture

Susan R.S. Gottesman, Jonathan Somma, Vladislav Tsiperson, Lisa Dresner, Usha Govindarajulu, Priyank Patel and Stacy W. Blain

Mol Cancer Res March 1 2019 17 (3) 669-675; DOI:10.1158/1541-7786.MCR-18-0188

Cancer Genes and Networks

Cancer Genes and Networks

Discovery and Characterization of Recurrent, Targetable ALK Fusions in Leiomyosarcoma

Lara E. Davis, Kevin D. Nusser, Joanna Przybyl, Janét Pittsenbarger, Nicolle E. Hofmann, Sushama Varma, Sujay Vennam, Maria Debiec-Rychter, Matt van de Rijn and Monika A. Davare

Mol Cancer Res March 1 2019 17 (3) 676-685; DOI:10.1158/1541-7786.MCR-18-1075
Cancer Genes and Networks

Epigenetic Regulation of Dlg1, via Kaiso, Alters Mitotic Spindle Polarity and Promotes Intestinal Tumorigenesis

Madeleine A. Young, Stephanie May, Angelos Damo, Young So Yoon, Man-Wook Hur, Wojiech Swat and Lee Parry

Mol Cancer Res March 1 2019 17 (3) 686-696; DOI:10.1158/1541-7786.MCR-18-0280
Cancer Genes and Networks

Growth Factor–Independent 1 Is a Tumor Suppressor Gene in Colorectal Cancer

Min-Shan Chen, Yuan-Hung Lo, Xi Chen, Christopher S. Williams, Jessica M. Donnelly, Zachary K. Criss II, Shreena Patel, Joann M. Butkus, Julien Dubrulle, Milton J. Finegold and Noah F. Shroyer

Mol Cancer Res March 1 2019 17 (3) 697-708; DOI:10.1158/1541-7786.MCR-18-0666
Cancer Genes and Networks | AuthorChoice

The Tumor Suppressor FBW7 and the Vitamin D Receptor Are Mutual Cofactors in Protein Turnover and Transcriptional Regulation

Reyhaneh Salehi-Tabar, Babak Memari, Hilary Wong, Vassil Dimitrov, Natacha Rochel and John H. White

Mol Cancer Res March 1 2019 17 (3) 709-719; DOI:10.1158/1541-7786.MCR-18-0991

Cancer “-omics”

Cancer “-omics”

CREBBP/EP300 Bromodomain Inhibition Affects the Proliferation of AR-Positive Breast Cancer Cell Lines

Veronica Garcia-Carpizo, Sergio Ruiz-Llorente, Jacinto Sarmentero, Ana González-Corpas and Maria J. Barrero

Mol Cancer Res March 1 2019 17 (3) 720-730; DOI:10.1158/1541-7786.MCR-18-0719
Cancer “-omics”

Multiclonality and Marked Branched Evolution of Low-Grade Endometrioid Endometrial Carcinoma

Lorena Lazo de la Vega, Mia C. Samaha, Kevin Hu, Nolan R. Bick, Javed Siddiqui, Daniel H. Hovelson, Chia-Jen Liu, Cody S. Carter, Kathleen R. Cho, Andrew P. Sciallis and Scott A. Tomlins

Mol Cancer Res March 1 2019 17 (3) 731-740; DOI:10.1158/1541-7786.MCR-18-1178

Cell Fate Decisions

Cell Fate Decisions | AuthorChoice

Ovarian Tumor Cell Expression of Claudin-4 Reduces Apoptotic Response to Paclitaxel

Christopher Breed, Douglas A. Hicks, Patricia G. Webb, Carly E. Galimanis, Benjamin G. Bitler, Kian Behbakht and Heidi K. Baumgartner

Mol Cancer Res March 1 2019 17 (3) 741-750; DOI:10.1158/1541-7786.MCR-18-0451
Cell Fate Decisions

Combinations of Tyrosine Kinase Inhibitor and ERAD Inhibitor Promote Oxidative Stress–Induced Apoptosis through ATF4 and KLF9 in Medullary Thyroid Cancer

Rozita Bagheri-Yarmand, Krishna M. Sinha, Ling Li, Yue Lu, Gilbert J. Cote, Steven I. Sherman and Robert F. Gagel

Mol Cancer Res March 1 2019 17 (3) 751-760; DOI:10.1158/1541-7786.MCR-18-0354

Genome Maintenance

Genome Maintenance

NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells

Ding Li, Yufei Luo, Xianling Chen, LingYu Zhang, Tingting Wang, Yingting Zhuang, Yingjuan Fan, Jianhua Xu, Yuanzhong Chen and Lixian Wu

Mol Cancer Res March 1 2019 17 (3) 761-772; DOI:10.1158/1541-7786.MCR-18-0523
Genome Maintenance

The Antitumor Drugs Trabectedin and Lurbinectedin Induce Transcription-Dependent Replication Stress and Genome Instability

Emanuela Tumini, Emilia Herrera-Moyano, Marta San Martín-Alonso, Sonia Barroso, Carlos M. Galmarini and Andrés Aguilera

Mol Cancer Res March 1 2019 17 (3) 773-782; DOI:10.1158/1541-7786.MCR-18-0575

Signal Transduction and Functional Imaging

Signal Transduction and Functional Imaging

CCL2 Is a Vascular Permeability Factor Inducing CCR2-Dependent Endothelial Retraction during Lung Metastasis

Marko Roblek, Darya Protsyuk, Paul F. Becker, Cristina Stefanescu, Christian Gorzelanny, Jesus F. Glaus Garzon, Lucia Knopfova, Mathias Heikenwalder, Bruno Luckow, Stefan W. Schneider and Lubor Borsig

Mol Cancer Res March 1 2019 17 (3) 783-793; DOI:10.1158/1541-7786.MCR-18-0530
Signal Transduction and Functional Imaging

Reactive Oxygen Species (ROS)-Inducing Triterpenoid Inhibits Rhabdomyosarcoma Cell and Tumor Growth through Targeting Sp Transcription Factors

Ravi Kasiappan, Indira Jutooru, Kumaravel Mohankumar, Keshav Karki, Alexandra Lacey and Stephen Safe

Mol Cancer Res March 1 2019 17 (3) 794-805; DOI:10.1158/1541-7786.MCR-18-1071

Tumor Microenvironment and Immunobiology

Tumor Microenvironment and Immunobiology

Interactions with Muscle Cells Boost Fusion, Stemness, and Drug Resistance of Prostate Cancer Cells

Berna Uygur, Evgenia Leikina, Kamran Melikov, Rafael Villasmil, Santosh K. Verma, Calvin P.H. Vary and Leonid V. Chernomordik

Mol Cancer Res March 1 2019 17 (3) 806-820; DOI:10.1158/1541-7786.MCR-18-0500
Tumor Microenvironment and Immunobiology

Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress

Victor Laurent, Aurélie Toulet, Camille Attané, Delphine Milhas, Stéphanie Dauvillier, Falek Zaidi, Emily Clement, Mathieu Cinato, Sophie Le Gonidec, Adrien Guérard, Camille Lehuédé, David Garandeau, Laurence Nieto, Edith Renaud-Gabardos, Anne-Catherine Prats, Philippe Valet, Bernard Malavaud and Catherine Muller

Mol Cancer Res March 1 2019 17 (3) 821-835; DOI:10.1158/1541-7786.MCR-18-0748