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Molecular Cancer Research
Molecular Cancer Research

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Table of Contents

Highlights

  • Highlights
    Highlights of This Issue
    Mol Cancer Res December 1 2019 17 (12) 2341-2341;

Cancer Genes and Networks

  • Cancer Genes and Networks
    Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells
    Alexandra E. Albert, Sally J. Adua, Wesley L. Cai, Anna Arnal-Estapé, Gary W. Cline, Zongzhi Liu, Minghui Zhao, Paul D. Cao, Malaiyalam Mariappan and Don X. Nguyen
    Mol Cancer Res December 1 2019 17 (12) 2343-2355; DOI:10.1158/1541-7786.MCR-19-0245

  • Cancer Genes and Networks
    Distinct Roles for BET Family Members in Estrogen Receptor α Enhancer Function and Gene Regulation in Breast Cancer Cells
    Shino Murakami, Rui Li, Anusha Nagari, Minho Chae, Cristel V. Camacho and W. Lee Kraus
    Mol Cancer Res December 1 2019 17 (12) 2356-2368; DOI:10.1158/1541-7786.MCR-19-0393

  • Cancer Genes and Networks
    SIX1 Regulates Aberrant Endometrial Epithelial Cell Differentiation and Cancer Latency Following Developmental Estrogenic Chemical Exposure
    Alisa A. Suen, Wendy N. Jefferson, Charles E. Wood and Carmen J. Williams
    Mol Cancer Res December 1 2019 17 (12) 2369-2382; DOI:10.1158/1541-7786.MCR-19-0475

  • Cancer Genes and Networks
    The Notch Pathway Promotes Osteosarcoma Progression through Activation of Ephrin Reverse Signaling
    Ling Yu, Kezhou Xia, Tian Gao, Jingteng Chen, Zhengpei Zhang, Xiangran Sun, Bruno M. Simões, Rachel Eyre, Zhengfu Fan, Weichun Guo and Robert B. Clarke
    Mol Cancer Res December 1 2019 17 (12) 2383-2394; DOI:10.1158/1541-7786.MCR-19-0493

  • Cancer Genes and Networks
    Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression
    Sanjay Chandrasekaran, Maiko Sasaki, Christopher D. Scharer, Haydn T. Kissick, Dillon G. Patterson, Kelly R. Magliocca, John T. Seykora, Bishu Sapkota, David A. Gutman, Lee A. Cooper, Gregory B. Lesinski, Edmund K. Waller, Susan N. Thomas, Sergei V. Kotenko, Jeremy M. Boss, Carlos S. Moreno, Robert A. Swerlick and Brian P. Pollack
    Mol Cancer Res December 1 2019 17 (12) 2395-2409; DOI:10.1158/1541-7786.MCR-19-0545

Cancer “-omics”

  • Cancer “-omics” | AuthorChoice
    Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma
    Kate Megquier, Jason Turner-Maier, Ross Swofford, Jong-Hyuk Kim, Aaron L. Sarver, Chao Wang, Sharadha Sakthikumar, Jeremy Johnson, Michele Koltookian, Mitzi Lewellen, Milcah C. Scott, Ashley J. Schulte, Luke Borst, Noriko Tonomura, Jessica Alfoldi, Corrie Painter, Rachael Thomas, Elinor K. Karlsson, Matthew Breen, Jaime F. Modiano, Ingegerd Elvers and Kerstin Lindblad-Toh
    Mol Cancer Res December 1 2019 17 (12) 2410-2421; DOI:10.1158/1541-7786.MCR-19-0221

  • Cancer “-omics”
    Outcome-Related Differences in Gene Expression Profiles of High-Grade Serous Ovarian Cancers Following Neoadjuvant Chemotherapy
    David Octeau, Roy Kessous, Kathleen Klein, Liron Kogan, Manuella Pelmus, Alex Ferenczy, Celia M.T. Greenwood, Leon C. Van Kempen, Shannon Salvador, Susie Lau, Patricia N. Tonin, Amber Yasmeen and Walter H. Gotlieb
    Mol Cancer Res December 1 2019 17 (12) 2422-2431; DOI:10.1158/1541-7786.MCR-19-0398

  • Cancer “-omics”
    Genetic and Epigenetic Characterization of Growth Hormone–Secreting Pituitary Tumors
    Niko Välimäki, Camilla Schalin-Jäntti, Atte Karppinen, Anders Paetau, Leena Kivipelto, Lauri A. Aaltonen and Auli Karhu
    Mol Cancer Res December 1 2019 17 (12) 2432-2443; DOI:10.1158/1541-7786.MCR-19-0434

Cell Fate Decisions

  • Cell Fate Decisions
    The Zinc-Finger AN1-Type Domain 2a Gene Acts as a Regulator of Cell Survival in Human Melanoma: Role of E3-Ligase cIAP2
    Sofia Pizzato Scomazzon, Anna Riccio, Silvia Santopolo, Giulia Lanzilli, Marta Coccia, Antonio Rossi and M. Gabriella Santoro
    Mol Cancer Res December 1 2019 17 (12) 2444-2456; DOI:10.1158/1541-7786.MCR-19-0243

  • Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814
    Cell Fate Decisions
    Therapeutic Implications of p53 Status on Cancer Cell Fate Following Exposure to Ionizing Radiation and the DNA-PK Inhibitor M3814
    Qing Sun, Yige Guo, Xiaohong Liu, Frank Czauderna, Michael I. Carr, Frank T. Zenke, Andree Blaukat and Lyubomir T. Vassilev
    Mol Cancer Res December 1 2019 17 (12) 2457-2468; DOI:10.1158/1541-7786.MCR-19-0362

  • Cell Fate Decisions
    Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2
    Rui Wang, Hongwei Liu, Yingying Shao, Kailong Wang, Shuangshuang Yin, Yuling Qiu, Honghua Wu, Erwei Liu, Tao Wang, Xiumei Gao and Haiyang Yu
    Mol Cancer Res December 1 2019 17 (12) 2469-2479; DOI:10.1158/1541-7786.MCR-19-0553

Genome Maintenance

  • Genome Maintenance
    Functional Loss of ATRX and TERC Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells
    Mindy K. Graham, Jiyoung Kim, Joseph Da, Jacqueline A. Brosnan-Cashman, Anthony Rizzo, Javier A. Baena Del Valle, Lionel Chia, Michael Rubenstein, Christine Davis, Qizhi Zheng, Leslie Cope, Michael Considine, Michael C. Haffner, Angelo M. De Marzo, Alan K. Meeker and Christopher M. Heaphy
    Mol Cancer Res December 1 2019 17 (12) 2480-2491; DOI:10.1158/1541-7786.MCR-19-0654

Metabolism

  • Metabolism
    A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability
    Isabelle Sirois, Adriana Aguilar-Mahecha, Josiane Lafleur, Emma Fowler, Viet Vu, Michelle Scriver, Marguerite Buchanan, Catherine Chabot, Aparna Ramanathan, Banujan Balachandran, Stéphanie Légaré, Ewa Przybytkowski, Cathy Lan, Urszula Krzemien, Luca Cavallone, Olga Aleynikova, Cristiano Ferrario, Marie-Christine Guilbert, Naciba Benlimame, Amine Saad, Moulay Alaoui-Jamali, Horace Uri Saragovi, Sylvia Josephy, Ciara O'Flanagan, Stephen D. Hursting, Vincent R. Richard, René P. Zahedi, Christoph H. Borchers, Eric Bareke, Sheida Nabavi, Peter Tonellato, Josée-Anne Roy, André Robidoux, Elizabeth A. Marcus, Catalin Mihalcioiu, Jacek Majewski and Mark Basik
    Mol Cancer Res December 1 2019 17 (12) 2492-2507; DOI:10.1158/1541-7786.MCR-19-0264

  • Metabolism
    Prostate Tumor Cell–Derived IL1β Induces an Inflammatory Phenotype in Bone Marrow Adipocytes and Reduces Sensitivity to Docetaxel via Lipolysis-Dependent Mechanisms
    Mackenzie K. Herroon, Jonathan D. Diedrich, Erandi Rajagurubandara, Carly Martin, Krishna R. Maddipati, Seongho Kim, Elisabeth I. Heath, James Granneman and Izabela Podgorski
    Mol Cancer Res December 1 2019 17 (12) 2508-2521; DOI:10.1158/1541-7786.MCR-19-0540

RNA Biology

  • RNA Biology
    Functional Analysis of Aberrantly Spliced Caspase8 Variants in Adult T-Cell Leukemia Cells
    Kazumi Nakano, Masako Iwanaga, Atae Utsunomiya, Kaoru Uchimaru and Toshiki Watanabe
    Mol Cancer Res December 1 2019 17 (12) 2522-2536; DOI:10.1158/1541-7786.MCR-19-0313

Tumor Microenvironment and Immunobiology

  • Tumor Microenvironment and Immunobiology
    Serum CD95L Level Correlates with Tumor Immune Infiltration and Is a Positive Prognostic Marker for Advanced High-Grade Serous Ovarian Cancer
    Thibault De La Motte Rouge, Julien Corné, Aurélie Cauchois, Marie Le Boulch, Clotilde Poupon, Sébastien Henno, Nathalie Rioux-Leclercq, Estelle Le Pabic, Bruno Laviolle, Véronique Catros, Jean Levêque, Alain Fautrel, Matthieu Le Gallo, Patrick Legembre and Vincent Lavoué
    Mol Cancer Res December 1 2019 17 (12) 2537-2548; DOI:10.1158/1541-7786.MCR-19-0449

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Molecular Cancer Research: 17 (12)
December 2019
Volume 17, Issue 12
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Issue Highlights

  • Distinct Roles for BET Family Members in Estrogen Receptor α Enhancer Function and Gene Regulation in Breast Cancer Cells
  • Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells
  • SIX1 Regulates Aberrant Endometrial Epithelial Cell Differentiation and Cancer Latency Following Developmental Estrogenic Chemical Exposure
  • A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability

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  • Cancer “-omics”
  • Cell Fate Decisions
  • Genome Maintenance
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  • RNA Biology
  • Tumor Microenvironment and Immunobiology
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Molecular Cancer Research
eISSN: 1557-3125
ISSN: 1541-7786

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