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Table of Contents

Highlights

Highlights

Highlights of This Issue

Mol Cancer Res April 1 2018 16 (4) 565-565;

Review

Review

The Long (lncRNA) and Short (miRNA) of It: TGFβ-Mediated Control of RNA-Binding Proteins and Noncoding RNAs

Harinarayanan Janakiraman, Reniqua P. House, Vamsi K. Gangaraju, J. Alan Diehl, Philip H. Howe and Viswanathan Palanisamy

Mol Cancer Res April 1 2018 16 (4) 567-579; DOI:10.1158/1541-7786.MCR-17-0547

Rapid Impact

Rapid Impact

BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-Mesenchymal Transition

Guillaume P. Andrieu and Gerald V. Denis

Mol Cancer Res April 1 2018 16 (4) 580-586; DOI:10.1158/1541-7786.MCR-17-0568

Cell Cycle and Senescence

Cell Cycle and Senescence

Mitotically-Associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer

Kirsten M. Tracy, Coralee E. Tye, Prachi N. Ghule, Heidi L.H. Malaby, Jason Stumpff, Janet L. Stein, Gary S. Stein and Jane B. Lian

Mol Cancer Res April 1 2018 16 (4) 587-598; DOI:10.1158/1541-7786.MCR-17-0548

Cell Death and Survival

Cell Death and Survival

Foxo-dependent Par-4 Upregulation Prevents Long-term Survival of Residual Cells Following PI3K–Akt Inhibition

Jeffrey S. Damrauer, Stephanie N. Phelps, Katie Amuchastegui, Ryan Lupo, Nathaniel W. Mabe, Andrea Walens, Benjamin R. Kroger and James V. Alvarez

Mol Cancer Res April 1 2018 16 (4) 599-609; DOI:10.1158/1541-7786.MCR-17-0492

Chromatin, Epigenetics and RNA Regulation

Chromatin, Epigenetics and RNA Regulation

BRD1-Mediated Acetylation Promotes Integrin αV Gene Expression Via Interaction with Sulfatide

Qian Qian Cai, Yi Wei Dong, Bing Qi, Xiao-Ting Shao, Rong Wang, Zhong Yi Chen, Bao Mei He and Xing Zhong Wu

Mol Cancer Res April 1 2018 16 (4) 610-622; DOI:10.1158/1541-7786.MCR-17-0527
Chromatin, Epigenetics and RNA Regulation | AuthorChoice

Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma

Houliang Deng, Jianming Zeng, Ting Zhang, Longcai Gong, Hongjie Zhang, Edwin Cheung, Chris Jones and Gang Li

Mol Cancer Res April 1 2018 16 (4) 623-633; DOI:10.1158/1541-7786.MCR-17-0460

DNA Damage and Repair

DNA Damage and Repair | AuthorChoice

Overt Increase of Oxidative Stress and DNA Damage in Murine and Human Colitis and Colitis-Associated Neoplasia

Adrian Frick, Vineeta Khare, Gregor Paul, Michaela Lang, Franziska Ferk, Siegfried Knasmüller, Andrea Beer, Georg Oberhuber and Christoph Gasche

Mol Cancer Res April 1 2018 16 (4) 634-642; DOI:10.1158/1541-7786.MCR-17-0451

Genomics

Genomics

Multigene Profiling of CTCs in mCRPC Identifies a Clinically Relevant Prognostic Signature

Udit Singhal, Yugang Wang, James Henderson, Yashar S. Niknafs, Yuanyuan Qiao, Amy Gursky, Alexander Zaslavsky, Jae-Seung Chung, David C. Smith, R. Jeffrey Karnes, S. Laura Chang, Felix Y. Feng, Ganesh S. Palapattu, Russell S. Taichman, Arul M. Chinnaiyan, Scott A. Tomlins and Todd M. Morgan

Mol Cancer Res April 1 2018 16 (4) 643-654; DOI:10.1158/1541-7786.MCR-17-0539

Metabolism

Metabolism

Microenvironment-Derived Regulation of HIF Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme

Dieter Henrik Heiland, Annette Gaebelein, Melanie Börries, Jakob Wörner, Nils Pompe, Pamela Franco, Sabrina Heynckes, Mark Bartholomae, Darren Ó. hAilín, Maria Stella Carro, Marco Prinz, Stefan Weber, Irina Mader, Daniel Delev and Oliver Schnell

Mol Cancer Res April 1 2018 16 (4) 655-668; DOI:10.1158/1541-7786.MCR-17-0680

Oncogenes and Tumor Suppressors

Oncogenes and Tumor Suppressors

Characterization and Evidence of the miR-888 Cluster as a Novel Cancer Network in Prostate

Tsuyoshi Hasegawa, Garrison J. Glavich, Mary Pahuski, Aleena Short, O. John Semmes, Lifang Yang, Vitold Galkin, Richard Drake and Aurora Esquela-Kerscher

Mol Cancer Res April 1 2018 16 (4) 669-681; DOI:10.1158/1541-7786.MCR-17-0321
Oncogenes and Tumor Suppressors

The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer

Mei Ding, Theodorus H. Van der Kwast, Ravi N. Vellanki, Warren D. Foltz, Trevor D. McKee, Nahum Sonenberg, Pier P. Pandolfi, Marianne Koritzinsky and Bradly G. Wouters

Mol Cancer Res April 1 2018 16 (4) 682-695; DOI:10.1158/1541-7786.MCR-17-0696
Oncogenes and Tumor Suppressors

Methylation of the HOXA10 Promoter Directs miR-196b-5p–Dependent Cell Proliferation and Invasion of Gastric Cancer Cells

Linlin Shao, Zheng Chen, Dunfa Peng, Mohammed Soutto, Shoumin Zhu, Andreia Bates, Shutian Zhang and Wael El-Rifai

Mol Cancer Res April 1 2018 16 (4) 696-706; DOI:10.1158/1541-7786.MCR-17-0655

Signal Transduction

Signal Transduction

Cancer Stem Cell Phenotypes in ER⁺ Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes

Thu H. Truong, Hsiangyu Hu, Nuri A. Temiz, Kyla M. Hagen, Brian J. Girard, Nicholas J. Brady, Kathryn L. Schwertfeger, Carol A. Lange and Julie H. Ostrander

Mol Cancer Res April 1 2018 16 (4) 707-719; DOI:10.1158/1541-7786.MCR-17-0598
Signal Transduction | AuthorChoice

AR Expression in Breast Cancer CTCs Associates with Bone Metastases

Nicola Aceto, Aditya Bardia, Ben S. Wittner, Maria C. Donaldson, Ryan O'Keefe, Amanda Engstrom, Francesca Bersani, Yu Zheng, Valentine Comaills, Kira Niederhoffer, Huili Zhu, Olivia Mackenzie, Toshi Shioda, Dennis Sgroi, Ravi Kapur, David T. Ting, Beverly Moy, Sridhar Ramaswamy, Mehmet Toner, Daniel A. Haber and Shyamala Maheswaran

Mol Cancer Res April 1 2018 16 (4) 720-727; DOI:10.1158/1541-7786.MCR-17-0480
Signal Transduction

Agonist-induced CXCR4 and CB2 Heterodimerization Inhibits Gα13/RhoA-mediated Migration

Kisha A. Scarlett, El-Shaddai Z. White, Christopher J. Coke, Jada R. Carter, Latoya K. Bryant and Cimona V. Hinton

Mol Cancer Res April 1 2018 16 (4) 728-739; DOI:10.1158/1541-7786.MCR-16-0481

Correction

Correction | Free Article

Correction: Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival

Mol Cancer Res April 1 2018 16 (4) 740-741; DOI:10.1158/1541-7786.MCR-18-0186