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Molecular Cancer Research
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Cell Death and Survival

Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155

Michael D. Nyquist, Alexandra Corella, John Burns, Ilsa Coleman, Shuai Gao, Robin Tharakan, Luke Riggan, Changmeng Cai, Eva Corey, Peter S. Nelson and Elahe A. Mostaghel
Michael D. Nyquist
1Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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Alexandra Corella
1Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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John Burns
2Virginia Mason Medical Center, Seattle, Washington.
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Ilsa Coleman
1Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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Shuai Gao
3Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.
4Hematology-Oncology Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
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Robin Tharakan
1Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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Luke Riggan
1Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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Changmeng Cai
3Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.
4Hematology-Oncology Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
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Eva Corey
5Department of Urology, University of Washington, Seattle, Washington.
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Peter S. Nelson
1Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
5Department of Urology, University of Washington, Seattle, Washington.
6Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington.
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Elahe A. Mostaghel
6Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington.
7Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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  • For correspondence: emostagh@fredhutch.org
DOI: 10.1158/1541-7786.MCR-16-0315-T Published May 2017
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Article Information

Volume 15, Issue 5, pp. 521-531

DOI 
https://doi.org/10.1158/1541-7786.MCR-16-0315-T
PubMed 
28465296

Published By 
American Association for Cancer Research
Print ISSN 
1541-7786
Online ISSN 
1557-3125
History 
  • Received September 22, 2016
  • Revision received December 3, 2016
  • Accepted December 22, 2016
  • Published first January 24, 2017.

Article Versions

  • Previous version (January 24, 2017 - 12:58).
  • You are viewing the most recent version of this article.
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©2017 American Association for Cancer Research.

Author Information

  1. Michael D. Nyquist1,
  2. Alexandra Corella1,
  3. John Burns2,
  4. Ilsa Coleman1,
  5. Shuai Gao3,4,
  6. Robin Tharakan1,
  7. Luke Riggan1,
  8. Changmeng Cai3,4,
  9. Eva Corey5,
  10. Peter S. Nelson1,5,6, and
  11. Elahe A. Mostaghel6,7,*
  1. 1Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  2. 2Virginia Mason Medical Center, Seattle, Washington.
  3. 3Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.
  4. 4Hematology-Oncology Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  5. 5Department of Urology, University of Washington, Seattle, Washington.
  6. 6Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington.
  7. 7Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  1. ↵*Corresponding Author:
    Elahe A. Mostaghel, University of Washington, 1100 Fairview Avenue N, P.O. Box 19024, Seattle, WA 98109. Phone: 206-667-2746; Fax: 206-667-2917; E-mail: emostagh{at}fredhutch.org
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Molecular Cancer Research: 15 (5)
May 2017
Volume 15, Issue 5
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Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155
Michael D. Nyquist, Alexandra Corella, John Burns, Ilsa Coleman, Shuai Gao, Robin Tharakan, Luke Riggan, Changmeng Cai, Eva Corey, Peter S. Nelson and Elahe A. Mostaghel
Mol Cancer Res May 1 2017 (15) (5) 521-531; DOI: 10.1158/1541-7786.MCR-16-0315-T

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Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155
Michael D. Nyquist, Alexandra Corella, John Burns, Ilsa Coleman, Shuai Gao, Robin Tharakan, Luke Riggan, Changmeng Cai, Eva Corey, Peter S. Nelson and Elahe A. Mostaghel
Mol Cancer Res May 1 2017 (15) (5) 521-531; DOI: 10.1158/1541-7786.MCR-16-0315-T
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