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Table of Contents

Highlights

Highlights

Highlights of This Issue

Mol Cancer Res April 1 2017 15 (4) 359-359;

Review

Review | AuthorChoice

Revisiting Seed and Soil: Examining the Primary Tumor and Cancer Cell Foraging in Metastasis

Amber E. de Groot, Sounak Roy, Joel S. Brown, Kenneth J. Pienta and Sarah R. Amend

Mol Cancer Res April 1 2017 15 (4) 361-370; DOI:10.1158/1541-7786.MCR-16-0436

Cell Cycle and Senescence

Cell Cycle and Senescence

A Systematic Analysis of Negative Growth Control Implicates the DREAM Complex in Cancer Cell Dormancy

James MacDonald, Yudith Ramos-Valdes, Pirunthan Perampalam, Larissa Litovchick, Gabriel E. DiMattia and Frederick A. Dick

Mol Cancer Res April 1 2017 15 (4) 371-381; DOI:10.1158/1541-7786.MCR-16-0323-T

Cell Death and Survival

Cell Death and Survival

A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance

Lina Y. Dimberg, Christina G. Towers, Kian Behbakht, Taylor J. Hotz, Jihye Kim, Susan Fosmire, Christopher C. Porter, Aik-Choon Tan, Andrew Thorburn and Heide L. Ford

Mol Cancer Res April 1 2017 15 (4) 382-394; DOI:10.1158/1541-7786.MCR-16-0234
Cell Death and Survival

TNF Signaling through RIP1 Kinase Enhances SN38-Induced Death in Colon Adenocarcinoma

Lucia Cabal-Hierro and Peter J. O'Dwyer

Mol Cancer Res April 1 2017 15 (4) 395-404; DOI:10.1158/1541-7786.MCR-16-0329

Chromatin, Epigenetics, and RNA Regulation

Chromatin, Epigenetics, and RNA Regulation

EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma–Induced Epigenetic Suppression of Osteoblast Differentiation

Juraj Adamik, Shunqian Jin, Quanhong Sun, Peng Zhang, Kurt R. Weiss, Judith L. Anderson, Rebecca Silbermann, G. David Roodman and Deborah L. Galson

Mol Cancer Res April 1 2017 15 (4) 405-417; DOI:10.1158/1541-7786.MCR-16-0242-T

DNA Damage and Repair

DNA Damage and Repair

14-3-3σ Contributes to Radioresistance By Regulating DNA Repair and Cell Cycle via PARP1 and CHK2

Yifan Chen, Zhaomin Li, Zizheng Dong, Jenny Beebe, Ke Yang, Liwu Fu and Jian-Ting Zhang

Mol Cancer Res April 1 2017 15 (4) 418-428; DOI:10.1158/1541-7786.MCR-16-0366

Genomics

Genomics | AuthorChoice

Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue

Eileen Snowden, Warren Porter, Friedrich Hahn, Mitchell Ferguson, Frances Tong, Joel S. Parker, Aaron Middlebrook, Smita Ghanekar, W. Shannon Dillmore and Rainer Blaesius

Mol Cancer Res April 1 2017 15 (4) 429-438; DOI:10.1158/1541-7786.MCR-16-0286-T

Metabolism

Metabolism | AuthorChoice

Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues

Stefano Cacciatore, Giorgia Zadra, Clyde Bango, Kathryn L. Penney, Svitlana Tyekucheva, Oscar Yanes and Massimo Loda

Mol Cancer Res April 1 2017 15 (4) 439-447; DOI:10.1158/1541-7786.MCR-16-0262

Oncogenes and Tumor Suppressors

Oncogenes and Tumor Suppressors

miR-211-5p Suppresses Metastatic Behavior by Targeting SNAI1 in Renal Cancer

Kefeng Wang, Wei Jin, Peng Jin, Xiang Fei, Xia Wang and Xiaonan Chen

Mol Cancer Res April 1 2017 15 (4) 448-456; DOI:10.1158/1541-7786.MCR-16-0288
Oncogenes and Tumor Suppressors

Bone Microenvironment Changes in Latexin Expression Promote Chemoresistance

Mi Zhang, Mary Osisami, Jinlu Dai, Jill M. Keller, June Escara-Wilke, Atsushi Mizokami and Evan T. Keller

Mol Cancer Res April 1 2017 15 (4) 457-466; DOI:10.1158/1541-7786.MCR-16-0392
Oncogenes and Tumor Suppressors

Inflammatory Molecule, PSGL-1, Deficiency Activates Macrophages to Promote Colorectal Cancer Growth through NFκB Signaling

Jiangchao Li, Zeqi Zhou, Xiaohan Zhang, Li Zheng, Dan He, Yuxiang Ye, Qian-Qian Zhang, Cui-Ling Qi, Xiao-Dong He, Chen Yu, Chun-kui Shao, Liang Qiao and Lijing Wang

Mol Cancer Res April 1 2017 15 (4) 467-477; DOI:10.1158/1541-7786.MCR-16-0309

Signal Transduction

Signal Transduction

Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer

Jacob M. Smigiel, Neetha Parameswaran and Mark W. Jackson

Mol Cancer Res April 1 2017 15 (4) 478-488; DOI:10.1158/1541-7786.MCR-16-0337
Signal Transduction | AuthorChoice

IGF-1 Receptor Modulates FoxO1-Mediated Tamoxifen Response in Breast Cancer Cells

Ali Vaziri-Gohar, Yan Zheng and Kevin D. Houston

Mol Cancer Res April 1 2017 15 (4) 489-497; DOI:10.1158/1541-7786.MCR-16-0176