Molecular Cancer Research: 15 (1)

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Highlights of This Issue

Mol Cancer Res January 1 2017 15 (1) 1-1;

Cell Cycle and Senescence

Cell Cycle and Senescence

Senescent Carcinoma-Associated Fibroblasts Upregulate IL8 to Enhance Prometastatic Phenotypes

Tao Wang, Faiyaz Notta, Roya Navab, Joella Joseph, Emin Ibrahimov, Jing Xu, Chang-Qi Zhu, Ayelet Borgida, Steven Gallinger and Ming-Sound Tsao

Mol Cancer Res January 1 2017 15 (1) 3-14; DOI:10.1158/1541-7786.MCR-16-0192

Cell Death and Survival

Cell Death and Survival

ECM Composition and Rheology Regulate Growth, Motility, and Response to Photodynamic Therapy in 3D Models of Pancreatic Ductal Adenocarcinoma

Gwendolyn M. Cramer, Dustin P. Jones, Hamid El-Hamidi and Jonathan P. Celli

Mol Cancer Res January 1 2017 15 (1) 15-25; DOI:10.1158/1541-7786.MCR-16-0260
Cell Death and Survival

Autophagy Induction Results in Enhanced Anoikis Resistance in Models of Peritoneal Disease

James L. Chen, Jason David, Douglas Cook-Spaeth, Sydney Casey, David Cohen, Karuppaiyah Selvendiran, Tanios Bekaii-Saab and John L. Hays

Mol Cancer Res January 1 2017 15 (1) 26-34; DOI:10.1158/1541-7786.MCR-16-0200-T

Chromatin, Epigenetics, and RNA Regulation

Chromatin, Epigenetics, and RNA Regulation

Exploitation of Castration-Resistant Prostate Cancer Transcription Factor Dependencies by the Novel BET Inhibitor ABBV-075

Emily J. Faivre, Denise Wilcox, Xiaoyu Lin, Paul Hessler, Maricel Torrent, Wei He, Tamar Uziel, Daniel H. Albert, Keith McDaniel, Warren Kati and Yu Shen

Mol Cancer Res January 1 2017 15 (1) 35-44; DOI:10.1158/1541-7786.MCR-16-0221

DNA Damage and Repair

DNA Damage and Repair

AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers

Kavitha Balaji, Smruthi Vijayaraghavan, Lixia Diao, Pan Tong, Youhong Fan, Jason P.W. Carey, Tuyen N. Bui, Steve Warner, John V. Heymach, Kelly K. Hunt, Jing Wang, Lauren Averett Byers and Khandan Keyomarsi

Mol Cancer Res January 1 2017 15 (1) 45-58; DOI:10.1158/1541-7786.MCR-16-0157

Signal Transduction

Signal Transduction

Interplay between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediates Castration Resistance

Yang Zhan, Guanyi Zhang, Xiaojie Wang, Yanfeng Qi, Shanshan Bai, Dongying Li, Tianfang Ma, Oliver Sartor, Erik K. Flemington, Haitao Zhang, Peng Lee and Yan Dong

Mol Cancer Res January 1 2017 15 (1) 59-68; DOI:10.1158/1541-7786.MCR-16-0236
Signal Transduction

Src Family Kinases Are Regulated in Multiple Myeloma Cells by Phosphatase of Regenerating Liver-3

Pegah Abdollahi, Esten N. Vandsemb, Magnus A. Hjort, Kristine Misund, Toril Holien, Anne-Marit Sponaas, Torstein B. Rø, Tobias S. Slørdahl and Magne Børset

Mol Cancer Res January 1 2017 15 (1) 69-77; DOI:10.1158/1541-7786.MCR-16-0212
Signal Transduction

Exosomes Promote Ovarian Cancer Cell Invasion through Transfer of CD44 to Peritoneal Mesothelial Cells

Koji Nakamura, Kenjiro Sawada, Yasuto Kinose, Akihiko Yoshimura, Aska Toda, Erika Nakatsuka, Kae Hashimoto, Seiji Mabuchi, Ken-ichirou Morishige, Hirohisa Kurachi, Ernst Lengyel and Tadashi Kimura

Mol Cancer Res January 1 2017 15 (1) 78-92; DOI:10.1158/1541-7786.MCR-16-0191
Signal Transduction

Exosomal Annexin II Promotes Angiogenesis and Breast Cancer Metastasis

Sayantan Maji, Pankaj Chaudhary, Irina Akopova, Phung M. Nguyen, Richard J. Hare, Ignacy Gryczynski and Jamboor K. Vishwanatha

Mol Cancer Res January 1 2017 15 (1) 93-105; DOI:10.1158/1541-7786.MCR-16-0163
Signal Transduction

Overcoming EGFR Bypass Signal-Induced Acquired Resistance to ALK Tyrosine Kinase Inhibitors in ALK-Translocated Lung Cancer

Masayoshi Miyawaki, Hiroyuki Yasuda, Tetsuo Tani, Junko Hamamoto, Daisuke Arai, Kota Ishioka, Keiko Ohgino, Shigenari Nukaga, Toshiyuki Hirano, Ichiro Kawada, Katsuhiko Naoki, Yuichiro Hayashi, Tomoko Betsuyaku and Kenzo Soejima

Mol Cancer Res January 1 2017 15 (1) 106-114; DOI:10.1158/1541-7786.MCR-16-0211

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Highlights

Cell Cycle and Senescence

Cell Death and Survival

Chromatin, Epigenetics, and RNA Regulation

DNA Damage and Repair

Signal Transduction

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