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Table of Contents

Highlights

Highlights

Highlights of This Issue

Mol Cancer Res April 1 2016 14 (4) 313-313;

Review

Review

Understanding TERT Promoter Mutations: A Common Path to Immortality

Robert J.A. Bell, H. Tomas Rube, Ana Xavier-Magalhães, Bruno M. Costa, Andrew Mancini, Jun S. Song and Joseph F. Costello

Mol Cancer Res April 1 2016 14 (4) 315-323; DOI:10.1158/1541-7786.MCR-16-0003

Rapid Impact

Rapid Impact

BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer

Irfan A. Asangani, Kari Wilder-Romans, Vijaya L. Dommeti, Pranathi M. Krishnamurthy, Ingrid J. Apel, June Escara-Wilke, Stephen R. Plymate, Nora M. Navone, Shaomeng Wang, Felix Y. Feng and Arul M. Chinnaiyan

Mol Cancer Res April 1 2016 14 (4) 324-331; DOI:10.1158/1541-7786.MCR-15-0472

Cell Cycle and Senescence

Cell Cycle and Senescence

Integrative Genomic Analyses Yield Cell-Cycle Regulatory Programs with Prognostic Value

Chao Cheng, Shaoke Lou, Erik H. Andrews, Matthew H. Ung and Frederick S. Varn

Mol Cancer Res April 1 2016 14 (4) 332-343; DOI:10.1158/1541-7786.MCR-15-0368

Cell Death and Survival

Cell Death and Survival

The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma

Wei Li, Alexa Cohen, Yin Sun, Jill Squires, Daniel Braas, Thomas G. Graeber, Lin Du, Gang Li, Zhen Li, Xiang Xu, Xufeng Chen and Jiaoti Huang

Mol Cancer Res April 1 2016 14 (4) 344-353; DOI:10.1158/1541-7786.MCR-15-0466

Chromatin, Epigenetics, and RNA Regulation

Chromatin, Epigenetics, and RNA Regulation

miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1

Masazumi Sakaguchi, Shigeo Hisamori, Nobu Oshima, Fumiaki Sato, Yohei Shimono and Yoshiharu Sakai

Mol Cancer Res April 1 2016 14 (4) 354-362; DOI:10.1158/1541-7786.MCR-15-0380

DNA Damage and Repair

DNA Damage and Repair

miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair

Jennifer R. Czochor, Parker Sulkowski and Peter M. Glazer

Mol Cancer Res April 1 2016 14 (4) 363-373; DOI:10.1158/1541-7786.MCR-15-0399

Genomics

Genomics

Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations

Daniella Bianchi-Frias, Ryan Basom, Jeffrey J. Delrow, Ilsa M. Coleman, Olga Dakhova, Xiaoyu Qu, Min Fang, Omar E. Franco, Nolan G. Ericson, Jason H. Bielas, Simon W. Hayward, Lawrence True, Colm Morrissey, Lisha Brown, Neil A. Bhowmick, David Rowley, Michael Ittmann and Peter S. Nelson

Mol Cancer Res April 1 2016 14 (4) 374-384; DOI:10.1158/1541-7786.MCR-15-0330

Oncogenes and Tumor Suppressors

Oncogenes and Tumor Suppressors

KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis

Amr M. Ghaleb, Enas A. Elkarim, Agnieszka B. Bialkowska and Vincent W. Yang

Mol Cancer Res April 1 2016 14 (4) 385-396; DOI:10.1158/1541-7786.MCR-15-0410

Signal Transduction

Signal Transduction

SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism

Bao Hoang, Yijiang Shi, Patrick J. Frost, Veena Mysore, Carolyne Bardeleben and Alan Lichtenstein

Mol Cancer Res April 1 2016 14 (4) 397-407; DOI:10.1158/1541-7786.MCR-15-0422