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Molecular Cancer Research
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Oncogenes and Tumor Suppressors

Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF

Jaclyn F. Hechtman, Ahmet Zehir, Rona Yaeger, Lu Wang, Sumit Middha, Tao Zheng, David M. Hyman, David Solit, Maria E. Arcila, Laetitia Borsu, Jinru Shia, Efsevia Vakiani, Leonard Saltz and Marc Ladanyi
Jaclyn F. Hechtman
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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  • For correspondence: hechtmaj@mskcc.org
Ahmet Zehir
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Rona Yaeger
2Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
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Lu Wang
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Sumit Middha
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Tao Zheng
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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David M. Hyman
2Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
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David Solit
2Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
3Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
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Maria E. Arcila
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Laetitia Borsu
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Jinru Shia
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Efsevia Vakiani
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Leonard Saltz
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Marc Ladanyi
1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
3Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
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DOI: 10.1158/1541-7786.MCR-15-0392-T Published March 2016
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ARTICLE USAGE: December 2015 to April 2021

AbstractFull-text HTMLPDF
Total262117981093

Cited By

Article Information

Volume 14, Issue 3, pp. 296-301

DOI 
https://doi.org/10.1158/1541-7786.MCR-15-0392-T
PubMed 
26660078

Published By 
American Association for Cancer Research
Print ISSN 
1541-7786
Online ISSN 
1557-3125
History 
  • Received September 14, 2015
  • Revision received November 24, 2015
  • Accepted November 29, 2015
  • Published first December 11, 2015.

Article Versions

  • Previous version (December 11, 2015 - 06:16).
  • Previous version (March 2, 2016 - 07:32).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2015 American Association for Cancer Research.

Author Information

  1. Jaclyn F. Hechtman1,*,
  2. Ahmet Zehir1,
  3. Rona Yaeger2,
  4. Lu Wang1,
  5. Sumit Middha1,
  6. Tao Zheng1,
  7. David M. Hyman2,
  8. David Solit2,3,
  9. Maria E. Arcila1,
  10. Laetitia Borsu1,
  11. Jinru Shia1,
  12. Efsevia Vakiani1,
  13. Leonard Saltz1, and
  14. Marc Ladanyi1,3
  1. 1Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  2. 2Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  3. 3Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  1. ↵*Corresponding Author:
    Jaclyn F Hechtman, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065. Phone: 212-639-8070; E-mail: hechtmaj{at}mskcc.org
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Molecular Cancer Research: 14 (3)
March 2016
Volume 14, Issue 3
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Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF
Jaclyn F. Hechtman, Ahmet Zehir, Rona Yaeger, Lu Wang, Sumit Middha, Tao Zheng, David M. Hyman, David Solit, Maria E. Arcila, Laetitia Borsu, Jinru Shia, Efsevia Vakiani, Leonard Saltz and Marc Ladanyi
Mol Cancer Res March 1 2016 (14) (3) 296-301; DOI: 10.1158/1541-7786.MCR-15-0392-T

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Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF
Jaclyn F. Hechtman, Ahmet Zehir, Rona Yaeger, Lu Wang, Sumit Middha, Tao Zheng, David M. Hyman, David Solit, Maria E. Arcila, Laetitia Borsu, Jinru Shia, Efsevia Vakiani, Leonard Saltz and Marc Ladanyi
Mol Cancer Res March 1 2016 (14) (3) 296-301; DOI: 10.1158/1541-7786.MCR-15-0392-T
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