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Table of Contents

Highlights

Highlights

Highlights of This Issue

Mol Cancer Res May 1 2015 13 (5) 807-807;

Cell Death and Survival

Cell Death and Survival

HuR Suppresses Fas Expression and Correlates with Patient Outcome in Liver Cancer

Haifeng Zhu, Zuzana Berkova, Rohit Mathur, Lalit Sehgal, Tamer Khashab, Rong-Hua Tao, Xue Ao, Lei Feng, Anita L. Sabichi, Boris Blechacz, Asif Rashid and Felipe Samaniego

Mol Cancer Res May 1 2015 13 (5) 809-818; DOI:10.1158/1541-7786.MCR-14-0241
Cell Death and Survival

Variants of Osteoprotegerin Lacking TRAIL Binding for Therapeutic Bone Remodeling in Osteolytic Malignancies

Jerome T. Higgs, John S. Jarboe, Joo Hyoung Lee, Diptiman Chanda, Carnellia M. Lee, Champion Deivanayagam and Selvarangan Ponnazhagan

Mol Cancer Res May 1 2015 13 (5) 819-827; DOI:10.1158/1541-7786.MCR-14-0492

Chromatin, Gene, and RNA Regulation

Chromatin, Gene, and RNA Regulation

The lncRNA DRAIC/PCAT29 Locus Constitutes a Tumor-Suppressive Nexus

Kouhei Sakurai, Brian J. Reon, Jordan Anaya and Anindya Dutta

Mol Cancer Res May 1 2015 13 (5) 828-838; DOI:10.1158/1541-7786.MCR-15-0016-T
Chromatin, Gene, and RNA Regulation

LncRNA Expression Discriminates Karyotype and Predicts Survival in B-Lymphoblastic Leukemia

Thilini R. Fernando, Norma I. Rodriguez-Malave, Ella V. Waters, Weihong Yan, David Casero, Giuseppe Basso, Martina Pigazzi and Dinesh S. Rao

Mol Cancer Res May 1 2015 13 (5) 839-851; DOI:10.1158/1541-7786.MCR-15-0006-T

DNA Damage and Repair

DNA Damage and Repair

Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins

Uday Bhanu Maachani, Tamalee Kramp, Ryan Hanson, Shuping Zhao, Orieta Celiku, Uma Shankavaram, Riccardo Colombo, Natasha J. Caplen, Kevin Camphausen and Anita Tandle

Mol Cancer Res May 1 2015 13 (5) 852-862; DOI:10.1158/1541-7786.MCR-14-0462-T

Genomics

Genomics

Detection of Tumor Suppressor Genes in Cancer Development by a Novel shRNA-Based Method

Johannes von Burstin, Sandra Diersch, Günter Schneider, Maximilian Reichert, Anil K. Rustgi and Roland M. Schmid

Mol Cancer Res May 1 2015 13 (5) 863-869; DOI:10.1158/1541-7786.MCR-14-0709
Genomics

Genome-Wide Profiling of TRACK Kidneys Shows Similarity to the Human ccRCC Transcriptome

Leiping Fu, Denise R. Minton, Tuo Zhang, David M. Nanus and Lorraine J. Gudas

Mol Cancer Res May 1 2015 13 (5) 870-878; DOI:10.1158/1541-7786.MCR-14-0423

Oncogenes and Tumor Suppressors

Oncogenes and Tumor Suppressors | AuthorChoice

Tumor Suppressor NF2 Blocks Cellular Migration by Inhibiting Ectodomain Cleavage of CD44

Monika Hartmann, Liseth M. Parra, Anne Ruschel, Sandra Böhme, Yong Li, Helen Morrison, Andreas Herrlich and Peter Herrlich

Mol Cancer Res May 1 2015 13 (5) 879-890; DOI:10.1158/1541-7786.MCR-15-0020-T
Oncogenes and Tumor Suppressors

Breast Cancer–Specific miR Signature Unique to Extracellular Vesicles Includes “microRNA-like” tRNA Fragments

Nicole Guzman, Kitty Agarwal, Dilip Asthagiri, Lianbo Yu, Motoyasu Saji, Matthew D. Ringel and Michael E. Paulaitis

Mol Cancer Res May 1 2015 13 (5) 891-901; DOI:10.1158/1541-7786.MCR-14-0533
Oncogenes and Tumor Suppressors

The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells

Perla El-Hage, Ambre Petitalot, Anne-Hélène Monsoro-Burq, Frédérique Maczkowiak, Keltouma Driouch, Etienne Formstecher, Jacques Camonis, Michèle Sabbah, Ivan Bièche, Rosette Lidereau and François Lallemand

Mol Cancer Res May 1 2015 13 (5) 902-912; DOI:10.1158/1541-7786.MCR-14-0180
Oncogenes and Tumor Suppressors | AuthorChoice

The Tumor Suppressor NKX3.1 Is Targeted for Degradation by DYRK1B Kinase

Liang-Nian Song, Jose Silva, Antonius Koller, Andrew Rosenthal, Emily I. Chen and Edward P. Gelmann

Mol Cancer Res May 1 2015 13 (5) 913-922; DOI:10.1158/1541-7786.MCR-14-0680

Signal Transduction

Signal Transduction

mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer

Valerie L. Sodi, Sakina Khaku, Raisa Krutilina, Luciana P. Schwab, David J. Vocadlo, Tiffany N. Seagroves and Mauricio J. Reginato

Mol Cancer Res May 1 2015 13 (5) 923-933; DOI:10.1158/1541-7786.MCR-14-0536
Signal Transduction

MAPK7 Regulates EMT Features and Modulates the Generation of CTCs

Sarah Javaid, Jianmin Zhang, Gromoslaw A. Smolen, Min Yu, Ben S. Wittner, Anurag Singh, Kshitij S. Arora, Marissa W. Madden, Rushil Desai, Matthew J. Zubrowski, Benjamin J. Schott, David T. Ting, Shannon L. Stott, Mehmet Toner, Shyamala Maheswaran, Toshi Shioda, Sridhar Ramaswamy and Daniel A. Haber

Mol Cancer Res May 1 2015 13 (5) 934-943; DOI:10.1158/1541-7786.MCR-14-0604
Signal Transduction

Aberrant LPL Expression, Driven by STAT3, Mediates Free Fatty Acid Metabolism in CLL Cells

Uri Rozovski, Srdana Grgurevic, Carlos Bueso-Ramos, David M. Harris, Ping Li, Zhiming Liu, Ji Yuan Wu, Preetesh Jain, William Wierda, Jan Burger, Susan O'Brien, Nitin Jain, Alessandra Ferrajoli, Michael J. Keating and Zeev Estrov

Mol Cancer Res May 1 2015 13 (5) 944-953; DOI:10.1158/1541-7786.MCR-14-0412